#Line number RuleID ViolationType Message Line #------------ #------------ # Validation for #144089 annotations in 144108 lines #------------ #Line number RuleID ViolationType Message Line #------------ # GO_AR:0000005 No ISS or ISS-related annotations to 'protein binding ; GO:0005515' Error count: 7 34954 GO_AR:0000005 Error No ISS or ISS-related annotations to 'protein binding ; GO:0005515' UniProtKB A2VDW9 IKZF3 GO:0005515 GO_REF:0000024 ISS UniProtKB:Q9UKT9 F Zinc finger protein Aiolos IKZF3|ZNFN1A3 protein taxon:9913 20191111 UniProt 58264 GO_AR:0000005 Error No ISS or ISS-related annotations to 'protein binding ; GO:0005515' UniProtKB E1BJ75 CRTAP GO:0005515 GO_REF:0000024 ISS UniProtKB:Q90830 F Cartilage associated protein CRTAP protein taxon:9913 20180925 UniProt 102727 GO_AR:0000005 Error No ISS or ISS-related annotations to 'protein binding ; GO:0005515' UniProtKB P08169 IGF2R GO:0005515 GO_REF:0000024 ISS UniProtKB:P11717 F Cation-independent mannose-6-phosphate receptor IGF2R|M6P protein taxon:9913 20091210 UniProt 104333 GO_AR:0000005 Error No ISS or ISS-related annotations to 'protein binding ; GO:0005515' UniProtKB P18341 TGFB1 GO:0005515 GO_REF:0000024 ISS UniProtKB:P01137 F Transforming growth factor beta-1 proprotein TGFB1 protein taxon:9913 20141202 AgBase 110340 GO_AR:0000005 Error No ISS or ISS-related annotations to 'protein binding ; GO:0005515' UniProtKB P80311 PPIB GO:0005515 GO_REF:0000024 ISS UniProtKB:P24367 F Peptidyl-prolyl cis-trans isomerase B PPIB protein taxon:9913 20180925 UniProt 130040 GO_AR:0000005 Error No ISS or ISS-related annotations to 'protein binding ; GO:0005515' UniProtKB Q3MHX6 OS9 GO:0005515 GO_REF:0000024 ISS UniProtKB:Q13438 F Protein OS-9 OS9 protein taxon:9913 20090907 UniProt 130490 GO_AR:0000005 Error No ISS or ISS-related annotations to 'protein binding ; GO:0005515' UniProtKB Q3SX24 FBXO6 GO:0005515 GO_REF:0000024 ISS UniProtKB:Q9QZN4 F F-box only protein 6 FBXO6|FBS2|FBX6 protein taxon:9913 20090903 UniProt #------------ # GO_AR:0000014 Valid GO term ID Error count: 12 101153 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0010867 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001013),has_agent(UBERON:0002107),occurs_in(UBERON:0001911) 101153 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0010867 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001013),has_agent(UBERON:0002107),occurs_in(UBERON:0001911) 101163 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0045542 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001013),has_agent(UBERON:0002107),occurs_in(UBERON:0001911) 101163 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0045542 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001013),has_agent(UBERON:0002107),occurs_in(UBERON:0001911) 101165 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0045723 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001911),has_agent(UBERON:0002107),occurs_in(UBERON:0001013) 101165 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0045723 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001911),has_agent(UBERON:0002107),occurs_in(UBERON:0001013) 101166 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0045723 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001013),has_agent(UBERON:0002107),occurs_in(UBERON:0001911) 101166 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0045723 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001013),has_agent(UBERON:0002107),occurs_in(UBERON:0001911) 101171 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0071073 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001911),has_agent(UBERON:0002107),occurs_in(UBERON:0001013) 101171 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0071073 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001911),has_agent(UBERON:0002107),occurs_in(UBERON:0001013) 101172 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:1900482 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001013),has_agent(UBERON:0002107),occurs_in(UBERON:0001911) 101172 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:1900482 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001013),has_agent(UBERON:0002107),occurs_in(UBERON:0001911) #------------ # GO_AR:0000003 Annotations to 'binding ; GO:0005488' and 'protein binding ; GO:0005515' should be made with IPI and an interactor in the 'with' field Warning count: 8 34954 GO_AR:0000003 Warning Annotations to 'binding' (GO:0005488) and 'protein binding' (GO:0005515) should be made with an IPI evidence code and the interactor in the 'with' field UniProtKB A2VDW9 IKZF3 GO:0005515 GO_REF:0000024 ISS UniProtKB:Q9UKT9 F Zinc finger protein Aiolos IKZF3|ZNFN1A3 protein taxon:9913 20191111 UniProt 58264 GO_AR:0000003 Warning Annotations to 'binding' (GO:0005488) and 'protein binding' (GO:0005515) should be made with an IPI evidence code and the interactor in the 'with' field UniProtKB E1BJ75 CRTAP GO:0005515 GO_REF:0000024 ISS UniProtKB:Q90830 F Cartilage associated protein CRTAP protein taxon:9913 20180925 UniProt 101935 GO_AR:0000003 Warning Annotations to 'binding' (GO:0005488) and 'protein binding' (GO:0005515) should be made with an IPI evidence code and the interactor in the 'with' field UniProtKB P04272 ANXA2 GO:0005515 PMID:18597635 TAS F Annexin A2 ANXA2|ANX2 protein taxon:9913 20140514 AgBase 102727 GO_AR:0000003 Warning Annotations to 'binding' (GO:0005488) and 'protein binding' (GO:0005515) should be made with an IPI evidence code and the interactor in the 'with' field UniProtKB P08169 IGF2R GO:0005515 GO_REF:0000024 ISS UniProtKB:P11717 F Cation-independent mannose-6-phosphate receptor IGF2R|M6P protein taxon:9913 20091210 UniProt 104333 GO_AR:0000003 Warning Annotations to 'binding' (GO:0005488) and 'protein binding' (GO:0005515) should be made with an IPI evidence code and the interactor in the 'with' field UniProtKB P18341 TGFB1 GO:0005515 GO_REF:0000024 ISS UniProtKB:P01137 F Transforming growth factor beta-1 proprotein TGFB1 protein taxon:9913 20141202 AgBase 110340 GO_AR:0000003 Warning Annotations to 'binding' (GO:0005488) and 'protein binding' (GO:0005515) should be made with an IPI evidence code and the interactor in the 'with' field UniProtKB P80311 PPIB GO:0005515 GO_REF:0000024 ISS UniProtKB:P24367 F Peptidyl-prolyl cis-trans isomerase B PPIB protein taxon:9913 20180925 UniProt 130040 GO_AR:0000003 Warning Annotations to 'binding' (GO:0005488) and 'protein binding' (GO:0005515) should be made with an IPI evidence code and the interactor in the 'with' field UniProtKB Q3MHX6 OS9 GO:0005515 GO_REF:0000024 ISS UniProtKB:Q13438 F Protein OS-9 OS9 protein taxon:9913 20090907 UniProt 130490 GO_AR:0000003 Warning Annotations to 'binding' (GO:0005488) and 'protein binding' (GO:0005515) should be made with an IPI evidence code and the interactor in the 'with' field UniProtKB Q3SX24 FBXO6 GO:0005515 GO_REF:0000024 ISS UniProtKB:Q9QZN4 F F-box only protein 6 FBXO6|FBS2|FBX6 protein taxon:9913 20090903 UniProt #------------ # GO_AR:0000008 No annotations should be made to uninformative high level terms Warning count: 2 110475 GO_AR:0000008 Warning Do not annotate to: GO:0005622 'intracellular' The term is considered to high level, as marked via the subset tag: gocheck_do_not_annotate UniProtKB P81287 ANXA5 GO:0005622 GO_REF:0000024 ISS UniProtKB:P08758 C Annexin A5 ANXA5|ANX5 protein taxon:9913 20061003 AgBase 122841 GO_AR:0000008 Warning Do not annotate to: GO:0005622 'intracellular' The term is considered to high level, as marked via the subset tag: gocheck_do_not_annotate UniProtKB Q2HJ92 PRKRA GO:0005622 GO_REF:0000024 ISS UniProtKB:Q9WTX2 C Interferon-inducible double-stranded RNA-dependent protein kinase activator A PRKRA protein taxon:9913 20070616 AgBase #------------ # GO_AR:0000014 Valid GO term ID Warning count: 3 10645 GO_AR:0000014 Warning The id 'GO:0006344' in the annotation is an alternate id for: GO:0070829 UniProtKB A0A3Q1M2B9 ARID1A GO:0006344 GO_REF:0000107 IEA UniProtKB:A2BH40|ensembl:ENSMUSP00000101517 P ARID domain-containing protein ARID1A protein taxon:9913 20200215 Ensembl 76030 GO_AR:0000014 Warning The id 'GO:0006344' in the annotation is an alternate id for: GO:0070829 UniProtKB F1MQB8 SIRT1 GO:0006344 GO_REF:0000107 IEA UniProtKB:Q96EB6|ensembl:ENSP00000212015 P Deacetylase sirtuin-type domain-containing protein SIRT1 protein taxon:9913 20200215 Ensembl 115397 GO_AR:0000014 Warning The id 'GO:0006344' in the annotation is an alternate id for: GO:0070829 UniProtKB Q0VC01 HDAC2 GO:0006344 GO_REF:0000107 IEA UniProtKB:Q92769|ensembl:ENSP00000430432 P Histone deacetylase 2 HDAC2 protein taxon:9913 20200215 Ensembl #------------