Table of contents

Report

Group: goa - Dataset: goa_human_isoform

SUMMARY

This report generated on 2020-03-23

Header From Original Association File

!gaf-version: 2.1
!
!The set of protein accessions included in this file is based on UniProt complete proteomes, which may provide more than one protein per gene.
!They include all Swiss-Prot entries for the species plus any TrEMBL entries that have an Ensembl DR line. The TrEMBL entries are likely to overlap with the Swiss-Prot entries or their isoforms.
!If a particular protein accession is not annotated with GO, then it will not appear in this file.
!
!Note that the annotation set in this file is filtered in order to reduce redundancy; the full, unfiltered set can be found in
!ftp://ftp.ebi.ac.uk/pub/databases/GO/goa/UNIPROT/goa_uniprot_all.gaf.gz
!
!Generated: 2020-02-24 22:18
!GO-version: http://purl.obolibrary.org/obo/go/releases/2020-02-20/extensions/go-plus.owl
!

Contents

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other

MESSAGES

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No 'NOT' annotations to 'protein binding ; GO:0005515'

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IEP and HEP usage is restricted to terms from the Biological Process ontology

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IPI should not be used with GO:0003824 catalytic activity or descendents

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No annotations should be made to uninformative high level terms

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ND evidence code should be to root nodes only, and no terms other than root nodes can have the evidence code ND

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Taxon-appropriate annotation check

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Dual species taxon check

Messages

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With/From: IC annotations require a With/From GO ID

gorule-0000017

IDA annotations must not have a With/From entry

gorule-0000018

IPI annotations require a With/From entry

gorule-0000020

Automatic repair of annotations to merged or obsoleted terms

Messages

gorule-0000027

Each identifier in GAF is valid

Messages

gorule-0000028

Aspect can only be one of C, P, F and should be repaired using the GO term

gorule-0000029

All IEAs over a year old are removed

gorule-0000030

Deprecated GO_REFs are not allowed

gorule-0000037

IBA annotations should ONLY be assigned_by GO_Central and have PMID:21873635 as a reference

gorule-0000039

Protein complexes can not be annotated to GO:0032991 (protein-containing complex) or its descendants

gorule-0000042

Qualifier: IKR evidence code requires a NOT qualifier

gorule-0000043

Check for valid combination of evidence code and GO_REF

gorule-0000046

The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms.

Messages

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Annotations to ISS, ISA and ISO should not be self-referential

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Group specific filter rules should be applied to annotations

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Object extensions should conform to the extensions-patterns.yaml file in metadata

other

Predictions

GO:0007186 G protein-coupled receptor signaling pathway AnnotationPropagation P GO:0016520 growth hormone-releasing hormone receptor activity NAS
GO:0007186 G protein-coupled receptor signaling pathway AnnotationPropagation P GO:0016520 growth hormone-releasing hormone receptor activity NAS
GO:0007186 G protein-coupled receptor signaling pathway AnnotationPropagation P GO:0016520 growth hormone-releasing hormone receptor activity NAS
GO:0120009 intermembrane lipid transfer AnnotationPropagation P GO:0120017 ceramide transfer activity IDA
GO:0045202 synapse AnnotationPropagation C GO:0098942 retrograde trans-synaptic signaling by trans-synaptic protein complex IDA
GO:0006508 proteolysis AnnotationPropagation P GO:0008236 serine-type peptidase activity IDA
GO:0016311 dephosphorylation AnnotationPropagation P GO:0046030 inositol trisphosphate phosphatase activity IDA
GO:0000122 negative regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
GO:0120009 intermembrane lipid transfer AnnotationPropagation P GO:0120020 cholesterol transfer activity ISS
GO:0015918 sterol transport AnnotationPropagation P GO:0120020 cholesterol transfer activity ISS
GO:0016311 dephosphorylation AnnotationPropagation P GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity IDA
GO:0007186 G protein-coupled receptor signaling pathway AnnotationPropagation P GO:0016520 growth hormone-releasing hormone receptor activity NAS
GO:0005739 mitochondrion AnnotationPropagation C GO:0042407 cristae formation IMP

Predictions (experimental)