This report generated on 2020-03-23
!gaf-version: 2.1
!
!The set of protein accessions included in this file is based on UniProt complete proteomes, which may provide more than one protein per gene.
!They include all Swiss-Prot entries for the species plus any TrEMBL entries that have an Ensembl DR line. The TrEMBL entries are likely to overlap with the Swiss-Prot entries or their isoforms.
!If a particular protein accession is not annotated with GO, then it will not appear in this file.
!
!Note that the annotation set in this file is filtered in order to reduce redundancy; the full, unfiltered set can be found in
!ftp://ftp.ebi.ac.uk/pub/databases/GO/goa/UNIPROT/goa_uniprot_all.gaf.gz
!
!Generated: 2020-02-24 22:14
!GO-version: http://purl.obolibrary.org/obo/go/releases/2020-02-20/extensions/go-plus.owl
!
GAF lines are parsed according to GAF 2.1 specifications
UniProtKB F1NJT3 FN1 GO:0008283 PMID:6178746 IDA P Fibronectin FN1 protein taxon:9031 20191105 AgBase CL:0000057 UniProtKB:F1NJT3
No 'NOT' annotations to 'protein binding ; GO:0005515'
IEP and HEP usage is restricted to terms from the Biological Process ontology
IPI should not be used with GO:0003824 catalytic activity or descendents
No annotations should be made to uninformative high level terms
UniProtKB A0A1D5PFN2 PALM GO:0005622 PMID:9813098 IDA C Paralemmin-1 PALM protein taxon:9031 20170202 AgBase part_of(UBERON:0000955) UniProtKB:A0A1D5PFN2
UniProtKB Q9YGL6 PALM GO:0005622 PMID:9813098 IDA C Paralemmin-1 PALM protein taxon:9031 20170202 AgBase part_of(UBERON:0000955) UniProtKB:Q9YGL6-2
UniProtKB Q9YGL6 PALM GO:0005622 PMID:9813098 IDA C Paralemmin-1 PALM protein taxon:9031 20170202 AgBase part_of(UBERON:0000955) UniProtKB:Q9YGL6-3
ND evidence code should be to root nodes only, and no terms other than root nodes can have the evidence code ND
Taxon-appropriate annotation check
UniProtKB A0A1D5NXV8 KDM5B GO:0061038 GO_REF:0000107 IEA UniProtKB:Q80Y84|ensembl:ENSMUSP00000038138 P Lysine-specific demethylase 5B KDM5B protein taxon:9031 20200215 Ensembl UniProtKB:A0A1D5NXV8
UniProtKB A0A1D5PX88 WNT3A GO:0021766 GO_REF:0000107 IEA UniProtKB:P27467|ensembl:ENSMUSP00000010044 P Protein Wnt WNT3A protein taxon:9031 20200215 Ensembl UniProtKB:A0A1D5PX88
UniProtKB A0A1I7Q3Z0 SRC GO:0060065 GO_REF:0000107 IEA UniProtKB:P05480|ensembl:ENSMUSP00000090237 P Tyrosine-protein kinase SRC protein taxon:9031 20200215 Ensembl UniProtKB:A0A1I7Q3Z0
UniProtKB A0A1L1RR94 PSAP GO:0060736 GO_REF:0000104 IEA UniRule:UR000342797 P Prosaposin PSAP protein taxon:9031 20200222 UniProt UniProtKB:A0A1L1RR94
UniProtKB A0A1L1RR94 PSAP GO:0060742 GO_REF:0000104 IEA UniRule:UR000342797 P Prosaposin PSAP protein taxon:9031 20200222 UniProt UniProtKB:A0A1L1RR94
UniProtKB A0A3Q2UE42 PSEN1 GO:0021795 GO_REF:0000107 IEA UniProtKB:P49769|ensembl:ENSMUSP00000098786 P Presenilin PSEN1 protein taxon:9031 20200215 Ensembl UniProtKB:A0A3Q2UE42
UniProtKB A0A452J863 HOXA5 GO:0048286 GO_REF:0000107 IEA UniProtKB:P09021|ensembl:ENSMUSP00000039012 P Homeobox domain-containing protein HOXA5 protein taxon:9031 20200215 Ensembl UniProtKB:A0A452J863
UniProtKB O93345 Lef-1 GO:0021542 PMID:15642085 ISS UniProtKB:P27782 P HMG box domain-containing protein Lef-1|LEF-1|LEF1 protein taxon:9031 20130311 AgBase UniProtKB:O93345
UniProtKB O93345 Lef-1 GO:0021766 GO_REF:0000024 ISS UniProtKB:P27782 P HMG box domain-containing protein Lef-1|LEF-1|LEF1 protein taxon:9031 20100127 AgBase UniProtKB:O93345
UniProtKB O93345 Lef-1 GO:0021766 PMID:15642085 ISS UniProtKB:P27782 P HMG box domain-containing protein Lef-1|LEF-1|LEF1 protein taxon:9031 20130311 AgBase UniProtKB:O93345
Dual species taxon check
With/From: IC annotations require a With/From GO ID
IDA annotations must not have a With/From entry
IPI annotations require a With/From entry
Each identifier in GAF is valid
UniProtKB F1NYI8 LONP2 GO:0005782 GO_REF:0000024 ISS UniProtKB:Q6TXI3 C Lon protease homolog 2, peroxisomal LONP2 protein taxon:9031 20061204 HGNC-UCL UniProtKB:F1NYI8
Aspect can only be one of C, P, F and should be repaired using the GO term
All IEAs over a year old are removed
Deprecated GO_REFs are not allowed
IBA annotations should ONLY be assigned_by GO_Central and have PMID:21873635 as a reference
Protein complexes can not be annotated to GO:0032991 (protein-containing complex) or its descendants
Qualifier: IKR evidence code requires a NOT qualifier
Check for valid combination of evidence code and GO_REF
The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms.
UniProtKB A0A1D5NXU2 FGFR2 GO:0042803 GO_REF:0000107 IEA UniProtKB:P21802|ensembl:ENSP00000410294 F Fibroblast growth factor receptor FGFR2 protein taxon:9031 20200215 Ensembl UniProtKB:A0A1D5NXU2
UniProtKB A0A1D5NZ26 TAF1B GO:0042803 GO_REF:0000107 IEA UniProtKB:Q9NZI5|ensembl:ENSP00000324693 F CP2 domain-containing protein TAF1B protein taxon:9031 20200215 Ensembl UniProtKB:A0A1D5NZ26
UniProtKB A0A1D5P127 KCNC4 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein KCNC4 protein taxon:9031 20200222 InterPro UniProtKB:A0A1D5P127
UniProtKB A0A1D5P3Y5 KCTD7 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein KCTD7 protein taxon:9031 20200222 InterPro UniProtKB:A0A1D5P3Y5
UniProtKB A0A1D5P723 TERF1 GO:0042803 GO_REF:0000002 IEA InterPro:IPR013867 F HTH myb-type domain-containing protein TERF1 protein taxon:9031 20200222 InterPro UniProtKB:A0A1D5P723
UniProtKB A0A1D5P8P4 KCND3 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein KCND3 protein taxon:9031 20200222 InterPro UniProtKB:A0A1D5P8P4
UniProtKB A0A1D5P9P3 ACTN1 GO:0042803 GO_REF:0000107 IEA UniProtKB:P12814|ensembl:ENSP00000377941 F Alpha-actinin-1 ACTN1 protein taxon:9031 20200215 Ensembl UniProtKB:A0A1D5P9P3
UniProtKB A0A1D5P9P3 ACTN1 GO:0042803 GO_REF:0000107 IEA UniProtKB:Q7TPR4|ensembl:ENSMUSP00000021554 F Alpha-actinin-1 ACTN1 protein taxon:9031 20200215 Ensembl UniProtKB:A0A1D5P9P3
UniProtKB A0A1D5PC94 HSF2 GO:0042803 PMID:9716376 IDA F HSF_DOMAIN domain-containing protein HSF2 protein taxon:9031 20170121 AgBase UniProtKB:A0A1D5PC94
UniProtKB A0A1D5PC94 HSF2 GO:0070207 PMID:9716376 IDA P HSF_DOMAIN domain-containing protein HSF2 protein taxon:9031 20170121 AgBase happens_during(GO:0010243),happens_during(GO:0014070) UniProtKB:A0A1D5PC94
UniProtKB A0A1D5PEQ3 KCTD17 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein KCTD17 protein taxon:9031 20200222 InterPro UniProtKB:A0A1D5PEQ3
UniProtKB A0A1D5PLW2 LDB1 GO:0042803 GO_REF:0000107 IEA UniProtKB:P70662|ensembl:ENSMUSP00000118546 F LID domain-containing protein LDB1 protein taxon:9031 20200215 Ensembl UniProtKB:A0A1D5PLW2
UniProtKB A0A1D5PLW2 LDB1 GO:0043621 GO_REF:0000107 IEA UniProtKB:P70662|ensembl:ENSMUSP00000118546 F LID domain-containing protein LDB1 protein taxon:9031 20200215 Ensembl UniProtKB:A0A1D5PLW2
UniProtKB A0A1D5PVF0 SIGMAR1 GO:0070207 GO_REF:0000107 IEA UniProtKB:Q99720|ensembl:ENSP00000277010 P Sigma non-opioid intracellular receptor 1 SIGMAR1 protein taxon:9031 20200215 Ensembl UniProtKB:A0A1D5PVF0
UniProtKB A0A1D5PY22 CRTC1 GO:0051289 GO_REF:0000002 IEA InterPro:IPR024783 P CREB regulated transcription coactivator 1 CRTC1 protein taxon:9031 20200222 InterPro UniProtKB:A0A1D5PY22
UniProtKB A0A1L1RMT7 CENPF GO:0042803 GO_REF:0000002 IEA InterPro:IPR019513 F Uncharacterized protein CENPF protein taxon:9031 20200222 InterPro UniProtKB:A0A1L1RMT7
UniProtKB A0A1L1RYG0 KCTD12 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein KCTD12 protein taxon:9031 20200222 InterPro UniProtKB:A0A1L1RYG0
UniProtKB A0A3Q2TTK5 KCNC2 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein KCNC2 protein taxon:9031 20200222 InterPro UniProtKB:A0A3Q2TTK5
UniProtKB A0A3Q2TTX5 LOC100859454 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein LOC100859454 protein taxon:9031 20200222 InterPro UniProtKB:A0A3Q2TTX5
UniProtKB A0A3Q2TX12 GPD1L2 GO:0042803 GO_REF:0000002 IEA InterPro:IPR017751 F Glycerol-3-phosphate dehydrogenase [NAD(+)] GPD1L2 protein taxon:9031 20200222 InterPro UniProtKB:A0A3Q2TX12
UniProtKB A0A3Q2TY64 LOC100859454 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein LOC100859454 protein taxon:9031 20200222 InterPro UniProtKB:A0A3Q2TY64
UniProtKB A0A3Q2U1G0 GSS GO:0042803 GO_REF:0000104 IEA UniRule:UR000131768 F Glutathione synthetase GSS protein taxon:9031 20200222 UniProt UniProtKB:A0A3Q2U1G0
UniProtKB A0A3Q2U986 KCNB2 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein KCNB2 protein taxon:9031 20200222 InterPro UniProtKB:A0A3Q2U986
UniProtKB A0A3Q2UBY8 CENPF GO:0042803 GO_REF:0000002 IEA InterPro:IPR019513 F Uncharacterized protein CENPF protein taxon:9031 20200222 InterPro UniProtKB:A0A3Q2UBY8
UniProtKB A0A3Q2UFI1 SLC39A13 GO:0042803 GO_REF:0000107 IEA UniProtKB:Q96H72|ensembl:ENSP00000354689 F Zinc transporter ZIP13 SLC39A13 protein taxon:9031 20200215 Ensembl UniProtKB:A0A3Q2UFI1
UniProtKB A0A3Q2UHS1 JAM3 GO:0042803 GO_REF:0000002 IEA InterPro:IPR042974 F Junctional adhesion molecule 3 JAM3 protein taxon:9031 20200222 InterPro UniProtKB:A0A3Q2UHS1
UniProtKB A0A3Q2UJ47 KCNC2 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein KCNC2 protein taxon:9031 20200222 InterPro UniProtKB:A0A3Q2UJ47
UniProtKB A0A3Q3ADB2 NECTIN3 GO:0042803 GO_REF:0000002 IEA InterPro:IPR033319 F Nectin cell adhesion molecule 3 NECTIN3 protein taxon:9031 20200222 InterPro UniProtKB:A0A3Q3ADB2
UniProtKB A0A3Q3AJJ9 NECTIN1 GO:0042803 GO_REF:0000002 IEA InterPro:IPR033314 F Nectin cell adhesion molecule 1 NECTIN1 protein taxon:9031 20200222 InterPro UniProtKB:A0A3Q3AJJ9
UniProtKB A0A3Q3AY63 LOC100859454 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein LOC100859454 protein taxon:9031 20200222 InterPro UniProtKB:A0A3Q3AY63
UniProtKB A0A452J7Q5 TNNC1 GO:0042803 GO_REF:0000107 IEA UniProtKB:P63316|ensembl:ENSP00000232975 F Troponin C, slow skeletal and cardiac muscles TNNC1 protein taxon:9031 20200215 Ensembl UniProtKB:A0A452J7Q5
UniProtKB A0A452J823 PTGS2 GO:0042803 GO_REF:0000107 IEA UniProtKB:Q05769|ensembl:ENSMUSP00000035065 F EGF-like domain-containing protein PTGS2 protein taxon:9031 20200215 Ensembl UniProtKB:A0A452J823
UniProtKB F1NBQ3 KCNC2 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein KCNC2 protein taxon:9031 20200222 InterPro UniProtKB:F1NBQ3
UniProtKB F1NJZ8 KCTD1 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein KCTD1 protein taxon:9031 20200222 InterPro UniProtKB:F1NJZ8
UniProtKB F1NSB3 JAM3 GO:0042803 GO_REF:0000002 IEA InterPro:IPR042974 F Junctional adhesion molecule 3 JAM3 protein taxon:9031 20200222 InterPro UniProtKB:F1NSB3
UniProtKB K4HVD3 KCTD15 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein KCTD15 protein taxon:9031 20200222 InterPro UniProtKB:K4HVD3
UniProtKB P05094 ACTN1 GO:0042803 PMID:8037676 IDA F Alpha-actinin-1 ACTN1 protein taxon:9031 20150407 AgBase UniProtKB:P05094-2
UniProtKB Q90979 IBR GO:0042803 PMID:8524232 IDA F Transcription factor IBR|F|NRF1 protein taxon:9031 20150422 AgBase UniProtKB:Q90979
Annotations to ISS, ISA and ISO should not be self-referential
UniProtKB P05122 CKB GO:0004111 GO_REF:0000024 ISS UniProtKB:P05122 F Creatine kinase B-type CKB protein taxon:9031 20150422 AgBase UniProtKB:P05122-2
UniProtKB P05122 CKB GO:0004111 GO_REF:0000024 ISS UniProtKB:P05122 F Creatine kinase B-type CKB protein taxon:9031 20150422 AgBase UniProtKB:P05122-3
UniProtKB P05122 CKB GO:0004111 GO_REF:0000024 ISS UniProtKB:P05122 F Creatine kinase B-type CKB protein taxon:9031 20150422 AgBase UniProtKB:P05122-4
UniProtKB P05122 CKB GO:0004111 GO_REF:0000024 ISS UniProtKB:P05122 F Creatine kinase B-type CKB protein taxon:9031 20150422 AgBase UniProtKB:P05122-5
UniProtKB P05122 CKB GO:0005615 GO_REF:0000024 ISS UniProtKB:P05122 C Creatine kinase B-type CKB protein taxon:9031 20150422 AgBase UniProtKB:P05122-2
UniProtKB P05122 CKB GO:0005615 GO_REF:0000024 ISS UniProtKB:P05122 C Creatine kinase B-type CKB protein taxon:9031 20150422 AgBase UniProtKB:P05122-3
UniProtKB P05122 CKB GO:0005615 GO_REF:0000024 ISS UniProtKB:P05122 C Creatine kinase B-type CKB protein taxon:9031 20150422 AgBase UniProtKB:P05122-4
UniProtKB P05122 CKB GO:0005615 GO_REF:0000024 ISS UniProtKB:P05122 C Creatine kinase B-type CKB protein taxon:9031 20150422 AgBase UniProtKB:P05122-5
UniProtKB P07812 PGR GO:0000790 GO_REF:0000024 ISS UniProtKB:P07812 C Progesterone receptor PGR|NR3C3 protein taxon:9031 20150427 AgBase part_of(UBERON:0000993),part_of(UBERON:0002107) UniProtKB:P07812-3
UniProtKB P07812 PGR GO:0005634 GO_REF:0000024 ISS UniProtKB:P07812 C Progesterone receptor PGR|NR3C3 protein taxon:9031 20151125 AgBase part_of(UBERON:0004804),part_of(UBERON:0004245),part_of(CL:0002132) UniProtKB:P07812-3
UniProtKB P07812 PGR GO:0005829 GO_REF:0000024 ISS UniProtKB:P07812 C Progesterone receptor PGR|NR3C3 protein taxon:9031 20150519 AgBase part_of(UBERON:0000993),part_of(UBERON:0002107),part_of(UBERON:0000955),part_of(UBERON:0001134) UniProtKB:P07812-3
UniProtKB P07812 PGR GO:0031490 GO_REF:0000024 ISS UniProtKB:P07812 F Progesterone receptor PGR|NR3C3 protein taxon:9031 20150427 AgBase UniProtKB:P07812-3
UniProtKB P07812 PGR GO:0032570 GO_REF:0000024 ISS UniProtKB:P07812 P Progesterone receptor PGR|NR3C3 protein taxon:9031 20150427 AgBase part_of(CL:0002132),part_of(UBERON:0004245) UniProtKB:P07812-3
UniProtKB P07812 PGR GO:0032993 GO_REF:0000024 ISS UniProtKB:P07812 C Progesterone receptor PGR|NR3C3 protein taxon:9031 20151125 AgBase UniProtKB:P07812-3
UniProtKB P07812 PGR GO:0043627 GO_REF:0000024 ISS UniProtKB:P07812 P Progesterone receptor PGR|NR3C3 protein taxon:9031 20150427 AgBase part_of(CL:0002132),part_of(UBERON:0004245) UniProtKB:P07812-3
UniProtKB P07812 PGR GO:1990239 GO_REF:0000024 ISS UniProtKB:P07812 F Progesterone receptor PGR|NR3C3 protein taxon:9031 20150519 AgBase occurs_in(UBERON:0000993),has_input(CHEBI:17026) UniProtKB:P07812-3
UniProtKB P12003 VCL GO:0005623 GO_REF:0000024 ISS UniProtKB:P12003 C Vinculin VCL|VINC1 protein taxon:9031 20150519 AgBase UniProtKB:P12003-1
UniProtKB P12003 VCL GO:0005886 GO_REF:0000024 ISS UniProtKB:P12003 C Vinculin VCL|VINC1 protein taxon:9031 20150519 AgBase UniProtKB:P12003-1
UniProtKB P12003 VCL GO:0005903 GO_REF:0000024 ISS UniProtKB:P12003 C Vinculin VCL|VINC1 protein taxon:9031 20150519 AgBase UniProtKB:P12003-1
UniProtKB P12003 VCL GO:0005915 GO_REF:0000024 ISS UniProtKB:P12003 C Vinculin VCL|VINC1 protein taxon:9031 20150519 AgBase UniProtKB:P12003-1
UniProtKB P12003 VCL GO:0090636 GO_REF:0000024 ISS UniProtKB:P12003 C Vinculin VCL|VINC1 protein taxon:9031 20150519 AgBase UniProtKB:P12003-1
UniProtKB P12003 VCL GO:0090637 GO_REF:0000024 ISS UniProtKB:P12003 C Vinculin VCL|VINC1 protein taxon:9031 20150519 AgBase UniProtKB:P12003-1
UniProtKB P12003 VCL GO:1990357 GO_REF:0000024 ISS UniProtKB:P12003 C Vinculin VCL|VINC1 protein taxon:9031 20150519 AgBase UniProtKB:P12003-1
Group specific filter rules should be applied to annotations
Object extensions should conform to the extensions-patterns.yaml file in metadata