Table of contents

Report

Group: genedb - Dataset: genedb_lmajor

SUMMARY

This report generated on 2020-03-23

Header From Original Association File

!gaf-version: 1.0

Contents

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other

MESSAGES

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GAF lines are parsed according to GAF 2.1 specifications

Messages

gorule-0000002

No 'NOT' annotations to 'protein binding ; GO:0005515'

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IEP and HEP usage is restricted to terms from the Biological Process ontology

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IPI should not be used with GO:0003824 catalytic activity or descendents

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No annotations should be made to uninformative high level terms

Messages

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ND evidence code should be to root nodes only, and no terms other than root nodes can have the evidence code ND

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Taxon-appropriate annotation check

Messages

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Dual species taxon check

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With/From: IC annotations require a With/From GO ID

Messages

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IDA annotations must not have a With/From entry

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IPI annotations require a With/From entry

Messages

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Automatic repair of annotations to merged or obsoleted terms

Messages

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Each identifier in GAF is valid

Messages

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Aspect can only be one of C, P, F and should be repaired using the GO term

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All IEAs over a year old are removed

gorule-0000030

Deprecated GO_REFs are not allowed

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IBA annotations should ONLY be assigned_by GO_Central and have PMID:21873635 as a reference

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Protein complexes can not be annotated to GO:0032991 (protein-containing complex) or its descendants

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Qualifier: IKR evidence code requires a NOT qualifier

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Check for valid combination of evidence code and GO_REF

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The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms.

Messages

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Annotations to ISS, ISA and ISO should not be self-referential

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Group specific filter rules should be applied to annotations

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Object extensions should conform to the extensions-patterns.yaml file in metadata

other

Predictions

GO:0006096 glycolytic process AnnotationPropagation P GO:0004743 pyruvate kinase activity RCA
GO:0005929 cilium AnnotationPropagation C GO:0035721 intraciliary retrograde transport ISO
GO:0070588 calcium ion transmembrane transport AnnotationPropagation P GO:0015085 calcium ion transmembrane transporter activity ISO
GO:0019722 calcium-mediated signaling AnnotationPropagation P GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity ISO
GO:0051209 release of sequestered calcium ion into cytosol AnnotationPropagation P GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity ISO
GO:0048016 inositol phosphate-mediated signaling AnnotationPropagation P GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity ISO
GO:0016311 dephosphorylation AnnotationPropagation P GO:0008254 3'-nucleotidase activity ISO
GO:0097502 mannosylation AnnotationPropagation P GO:0000026 alpha-1,2-mannosyltransferase activity ISO
GO:0005929 cilium AnnotationPropagation C GO:0035735 intraciliary transport involved in cilium assembly ISO
GO:0032774 RNA biosynthetic process AnnotationPropagation P GO:0003899 DNA-directed 5'-3' RNA polymerase activity ISM
GO:1903508 positive regulation of nucleic acid-templated transcription AnnotationPropagation P GO:0003713 transcription coactivator activity ISS
GO:0006508 proteolysis AnnotationPropagation P GO:0008234 cysteine-type peptidase activity EXP
GO:0055085 transmembrane transport AnnotationPropagation P GO:0042626 ATPase-coupled transmembrane transporter activity ISM
GO:0015798 myo-inositol transport AnnotationPropagation P GO:0005365 myo-inositol transmembrane transporter activity IDA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0005365 myo-inositol transmembrane transporter activity IDA
GO:0006508 proteolysis AnnotationPropagation P GO:0070012 oligopeptidase activity IMP
GO:0032774 RNA biosynthetic process AnnotationPropagation P GO:0003899 DNA-directed 5'-3' RNA polymerase activity ISO
GO:0006470 protein dephosphorylation AnnotationPropagation P GO:0004721 phosphoprotein phosphatase activity ISA
GO:0035335 peptidyl-tyrosine dephosphorylation AnnotationPropagation P GO:0004725 protein tyrosine phosphatase activity IDA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0016972 thiol oxidase activity ISO
GO:0005929 cilium AnnotationPropagation C GO:0035720 intraciliary anterograde transport ISO
GO:0006468 protein phosphorylation AnnotationPropagation P GO:0004674 protein serine/threonine kinase activity ISS
GO:0046854 phosphatidylinositol phosphorylation AnnotationPropagation P GO:0004430 1-phosphatidylinositol 4-kinase activity ISO
GO:1903830 magnesium ion transmembrane transport AnnotationPropagation P GO:0015095 magnesium ion transmembrane transporter activity EXP
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0003885 D-arabinono-1,4-lactone oxidase activity ISO
GO:0015755 fructose transmembrane transport AnnotationPropagation P GO:0005353 fructose transmembrane transporter activity ISO
GO:0000413 protein peptidyl-prolyl isomerization AnnotationPropagation P GO:0003755 peptidyl-prolyl cis-trans isomerase activity ISO
GO:0032774 RNA biosynthetic process AnnotationPropagation P GO:0003899 DNA-directed 5'-3' RNA polymerase activity ISO
GO:0032508 DNA duplex unwinding AnnotationPropagation P GO:0017116 single-stranded DNA helicase activity IDA
GO:0005929 cilium AnnotationPropagation C GO:0035735 intraciliary transport involved in cilium assembly ISO
GO:0055085 transmembrane transport AnnotationPropagation P GO:0042626 ATPase-coupled transmembrane transporter activity ISM
GO:1903506 regulation of nucleic acid-templated transcription AnnotationPropagation P GO:0003712 transcription coregulator activity ISO
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0004029 aldehyde dehydrogenase (NAD+) activity ISO
GO:0022900 electron transport chain AnnotationPropagation P GO:0004129 cytochrome-c oxidase activity ISO
GO:1902600 proton transmembrane transport AnnotationPropagation P GO:0004129 cytochrome-c oxidase activity ISO
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0030611 arsenate reductase activity IDA
GO:1901642 nucleoside transmembrane transport AnnotationPropagation P GO:0005337 nucleoside transmembrane transporter activity ISO
GO:0055085 transmembrane transport AnnotationPropagation P GO:0042626 ATPase-coupled transmembrane transporter activity ISM
GO:0006508 proteolysis AnnotationPropagation P GO:0016920 pyroglutamyl-peptidase activity IDA
GO:0006508 proteolysis AnnotationPropagation P GO:0008241 peptidyl-dipeptidase activity ISO
GO:0055085 transmembrane transport AnnotationPropagation P GO:0042626 ATPase-coupled transmembrane transporter activity ISM
GO:0035246 peptidyl-arginine N-methylation AnnotationPropagation P GO:0016274 protein-arginine N-methyltransferase activity IMP
GO:0055085 transmembrane transport AnnotationPropagation P GO:0042626 ATPase-coupled transmembrane transporter activity ISM
GO:0016310 phosphorylation AnnotationPropagation P GO:0051736 ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity ISA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0008398 sterol 14-demethylase activity ISO
GO:0070988 demethylation AnnotationPropagation P GO:0008398 sterol 14-demethylase activity ISO
GO:0006508 proteolysis AnnotationPropagation P GO:0004198 calcium-dependent cysteine-type endopeptidase activity ISM
GO:0097502 mannosylation AnnotationPropagation P GO:0000026 alpha-1,2-mannosyltransferase activity ISO
GO:0016310 phosphorylation AnnotationPropagation P GO:0016301 kinase activity ISO
GO:0006508 proteolysis AnnotationPropagation P GO:0070012 oligopeptidase activity ISO
GO:0034968 histone lysine methylation AnnotationPropagation P GO:0018024 histone-lysine N-methyltransferase activity ISO
GO:0090305 nucleic acid phosphodiester bond hydrolysis AnnotationPropagation P GO:0004527 exonuclease activity ISM
GO:0097502 mannosylation AnnotationPropagation P GO:0000009 alpha-1,6-mannosyltransferase activity ISO
GO:0046854 phosphatidylinositol phosphorylation AnnotationPropagation P GO:0016307 phosphatidylinositol phosphate kinase activity ISO
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0045174 glutathione dehydrogenase (ascorbate) activity IDA
GO:0098869 cellular oxidant detoxification AnnotationPropagation P GO:0045174 glutathione dehydrogenase (ascorbate) activity IDA
GO:0071806 protein transmembrane transport AnnotationPropagation P GO:0008320 protein transmembrane transporter activity ISA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0004155 6,7-dihydropteridine reductase activity IDA
GO:0032774 RNA biosynthetic process AnnotationPropagation P GO:0003899 DNA-directed 5'-3' RNA polymerase activity ISO
GO:0006508 proteolysis AnnotationPropagation P GO:0004222 metalloendopeptidase activity ISO
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0051920 peroxiredoxin activity IDA
GO:0098869 cellular oxidant detoxification AnnotationPropagation P GO:0051920 peroxiredoxin activity IDA
GO:0097502 mannosylation AnnotationPropagation P GO:0000026 alpha-1,2-mannosyltransferase activity ISO
GO:0005929 cilium AnnotationPropagation C GO:0035735 intraciliary transport involved in cilium assembly ISO
GO:0046854 phosphatidylinositol phosphorylation AnnotationPropagation P GO:0016303 1-phosphatidylinositol-3-kinase activity ISO
GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process AnnotationPropagation P GO:0016303 1-phosphatidylinositol-3-kinase activity ISO
GO:0005929 cilium AnnotationPropagation C GO:0035735 intraciliary transport involved in cilium assembly ISO
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0008137 NADH dehydrogenase (ubiquinone) activity ISS
GO:0055085 transmembrane transport AnnotationPropagation P GO:0042626 ATPase-coupled transmembrane transporter activity ISM
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0004352 glutamate dehydrogenase (NAD+) activity IDA
GO:0032508 DNA duplex unwinding AnnotationPropagation P GO:0003678 DNA helicase activity ISO
GO:0005929 cilium AnnotationPropagation C GO:0035735 intraciliary transport involved in cilium assembly ISO
GO:0016310 phosphorylation AnnotationPropagation P GO:0004305 ethanolamine kinase activity IDA
GO:0006508 proteolysis AnnotationPropagation P GO:0004197 cysteine-type endopeptidase activity ISM
GO:0006468 protein phosphorylation AnnotationPropagation P GO:0004672 protein kinase activity ISO
GO:0016310 phosphorylation AnnotationPropagation P GO:0008887 glycerate kinase activity RCA
GO:0005929 cilium AnnotationPropagation C GO:0035720 intraciliary anterograde transport ISO
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0051920 peroxiredoxin activity IDA
GO:0098869 cellular oxidant detoxification AnnotationPropagation P GO:0051920 peroxiredoxin activity IDA
GO:0016311 dephosphorylation AnnotationPropagation P GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity IDA
GO:0035725 sodium ion transmembrane transport AnnotationPropagation P GO:0005436 sodium:phosphate symporter activity ISO
GO:0005929 cilium AnnotationPropagation C GO:0035735 intraciliary transport involved in cilium assembly ISO
GO:0016311 dephosphorylation AnnotationPropagation P GO:0042577 lipid phosphatase activity IDA
GO:0006508 proteolysis AnnotationPropagation P GO:0008234 cysteine-type peptidase activity EXP
GO:0006508 proteolysis AnnotationPropagation P GO:0004181 metallocarboxypeptidase activity ISO
GO:1902600 proton transmembrane transport AnnotationPropagation P GO:0015506 nucleoside:proton symporter activity ISO
GO:1901642 nucleoside transmembrane transport AnnotationPropagation P GO:0015506 nucleoside:proton symporter activity ISO
GO:0090305 nucleic acid phosphodiester bond hydrolysis AnnotationPropagation P GO:0004527 exonuclease activity ISM
GO:0016567 protein ubiquitination AnnotationPropagation P GO:0004842 ubiquitin-protein transferase activity ISA
GO:0090305 nucleic acid phosphodiester bond hydrolysis AnnotationPropagation P GO:0004519 endonuclease activity ISO
GO:0006468 protein phosphorylation AnnotationPropagation P GO:0004674 protein serine/threonine kinase activity ISM
GO:0005929 cilium AnnotationPropagation C GO:0035735 intraciliary transport involved in cilium assembly ISO
GO:0055085 transmembrane transport AnnotationPropagation P GO:0042626 ATPase-coupled transmembrane transporter activity ISM
GO:0005739 mitochondrion AnnotationPropagation C GO:0006390 mitochondrial transcription ISO
GO:0015761 mannose transmembrane transport AnnotationPropagation P GO:0015578 mannose transmembrane transporter activity ISO
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0004657 proline dehydrogenase activity ISM
GO:0006259 DNA metabolic process AnnotationPropagation P GO:0004529 exodeoxyribonuclease activity ISM
GO:0090305 nucleic acid phosphodiester bond hydrolysis AnnotationPropagation P GO:0004529 exodeoxyribonuclease activity ISM
GO:0006468 protein phosphorylation AnnotationPropagation P GO:0004674 protein serine/threonine kinase activity ISM
GO:0000413 protein peptidyl-prolyl isomerization AnnotationPropagation P GO:0003755 peptidyl-prolyl cis-trans isomerase activity ISO
GO:0055085 transmembrane transport AnnotationPropagation P GO:0015205 nucleobase transmembrane transporter activity IDA
GO:0015851 nucleobase transport AnnotationPropagation P GO:0015205 nucleobase transmembrane transporter activity IDA
GO:0006657 CDP-choline pathway AnnotationPropagation P GO:0004142 diacylglycerol cholinephosphotransferase activity ISO
GO:0055085 transmembrane transport AnnotationPropagation P GO:0042626 ATPase-coupled transmembrane transporter activity ISM
GO:0097502 mannosylation AnnotationPropagation P GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity ISO
GO:0022900 electron transport chain AnnotationPropagation P GO:0008121 ubiquinol-cytochrome-c reductase activity ISS
GO:0050790 regulation of catalytic activity AnnotationPropagation P GO:0043763 UTP:glucose-1-phosphate uridylyltransferase regulator activity IDA
GO:1904659 glucose transmembrane transport AnnotationPropagation P GO:0055056 D-glucose transmembrane transporter activity ISO
GO:0055085 transmembrane transport AnnotationPropagation P GO:0042626 ATPase-coupled transmembrane transporter activity ISM
GO:0016310 phosphorylation AnnotationPropagation P GO:0050201 fucokinase activity IMP
GO:0005929 cilium AnnotationPropagation C GO:0035721 intraciliary retrograde transport ISO
GO:0006355 regulation of transcription, DNA-templated AnnotationPropagation P GO:0003700 DNA-binding transcription factor activity ISM
GO:0072334 UDP-galactose transmembrane transport AnnotationPropagation P GO:0005459 UDP-galactose transmembrane transporter activity IGI
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0016491 oxidoreductase activity ISO
GO:0005739 mitochondrion AnnotationPropagation C GO:0034551 mitochondrial respiratory chain complex III assembly ISO

Predictions (experimental)