• Summary (original)
• Report (original)
• OWLTools check (original)
• Predictions (original)
• Predictions (experimental) (original)

GAF summary

Found 22966 annotations in 22985 lines.

GAF Validation Summary Errors are reported first.

For rule GO_AR:0000014 (http://www.geneontology.org/GO.annotation_qc.shtml#GO_AR:0000014) Valid GO term ID, there are 2 violations with type Error.

For rule GO_AR:0000008 (http://www.geneontology.org/GO.annotation_qc.shtml#GO_AR:0000008) No annotations should be made to uninformative high level terms, there are 3 violations with type Warning.

GAF Prediction Summary

Found 10 predictions, see prediction file for details.

Used Ontology Summary

go/extensions/go-gaf    go/releases/2019-12-21/extensions/go-gaf.owl

Group: goa - Dataset: goa_chicken_isoform

SUMMARY

This report generated on 2020-01-01

• Associations: 22966
• Lines in file (incl headers): 29891
• Lines skipped: 6913

Header From Original Association File

!gaf-version: 2.1
!
!The set of protein accessions included in this file is based on UniProt complete proteomes, which may provide more than one protein per gene.
!They include all Swiss-Prot entries for the species plus any TrEMBL entries that have an Ensembl DR line. The TrEMBL entries are likely to overlap with the Swiss-Prot entries or their isoforms.
!If a particular protein accession is not annotated with GO, then it will not appear in this file.
!
!Note that the annotation set in this file is filtered in order to reduce redundancy; the full, unfiltered set can be found in
!ftp://ftp.ebi.ac.uk/pub/databases/GO/goa/UNIPROT/goa_uniprot_all.gaf.gz
!
!Generated: 2019-12-17 09:34
!GO-version: http://purl.obolibrary.org/obo/go/releases/2019-12-14/extensions/go-plus.owl
!

Contents

gorule-0000002

gorule-0000006

gorule-0000007

gorule-0000008

gorule-0000011

gorule-0000013

gorule-0000015

gorule-0000016

gorule-0000017

gorule-0000018

gorule-0000027

gorule-0000028

gorule-0000029

gorule-0000030

gorule-0000037

gorule-0000039

gorule-0000042

gorule-0000043

gorule-0000046

gorule-0000050

other

MESSAGES

gorule-0000002

No 'NOT' annotations to 'protein binding ; GO:0005515'

• total: 0

gorule-0000006

IEP and HEP usage is restricted to terms from the Biological Process ontology

• total: 0

gorule-0000007

IPI should not be used with GO:0003824 catalytic activity or descendents

• total: 0

gorule-0000008

No annotations should be made to uninformative high level terms

• total: 3

Messages

• WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms -- UniProtKB A0A1D5PFN2 PALM GO:0005622 PMID:9813098 IDA C Paralemmin-1 PALM protein taxon:9031 20170202 AgBase part_of(UBERON:0000955) UniProtKB:A0A1D5PFN2
• WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms -- UniProtKB Q9YGL6 PALM GO:0005622 PMID:9813098 IDA C Paralemmin-1 PALM protein taxon:9031 20170202 AgBase part_of(UBERON:0000955) UniProtKB:Q9YGL6-2
• WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms -- UniProtKB Q9YGL6 PALM GO:0005622 PMID:9813098 IDA C Paralemmin-1 PALM protein taxon:9031 20170202 AgBase part_of(UBERON:0000955) UniProtKB:Q9YGL6-3

gorule-0000011

ND evidence code should be to root nodes only, and no terms other than root nodes can have the evidence code ND

• total: 0

gorule-0000013

Taxon-appropriate annotation check

• total: 20

Messages

• WARNING - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- UniProtKB A0A1D5NXV8 KDM5B GO:0061038 GO_REF:0000107 IEA UniProtKB:Q80Y84|ensembl:ENSMUSP00000038138 P Lysine-specific demethylase 5B KDM5B protein taxon:9031 20191214 Ensembl UniProtKB:A0A1D5NXV8
• WARNING - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- UniProtKB A0A1D5PJQ6 WIPF2 GO:0000147 PMID:21873635 IBA PANTHER:PTN001506182|PomBase:SPAC4F10.15c|PomBase:SPBC13E7.09 P WH2 domain-containing protein WIPF2 protein taxon:9031 20170228 GO_Central UniProtKB:A0A1D5PJQ6
• WARNING - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- UniProtKB A0A1D5PJQ6 WIPF2 GO:0030479 PMID:21873635 IBA PANTHER:PTN001506182|PomBase:SPAC4F10.15c|PomBase:SPBC13E7.09|SGD:S000004329|SGD:S000005707 C WH2 domain-containing protein WIPF2 protein taxon:9031 20170228 GO_Central UniProtKB:A0A1D5PJQ6
• WARNING - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- UniProtKB A0A1D5PX88 WNT3A GO:0021766 GO_REF:0000107 IEA UniProtKB:P27467|ensembl:ENSMUSP00000010044 P Protein Wnt WNT3A protein taxon:9031 20191214 Ensembl UniProtKB:A0A1D5PX88
• WARNING - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- UniProtKB A0A1D5PZD9 TACC1 GO:0021987 PMID:21873635 IBA MGI:MGI:1341163|MGI:MGI:1928899|MGI:MGI:2443510|PANTHER:PTN000357964 P TACC_C domain-containing protein TACC1 protein taxon:9031 20170228 GO_Central UniProtKB:A0A1D5PZD9
• WARNING - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- UniProtKB A0A1I7Q3Z0 SRC GO:0060065 GO_REF:0000107 IEA UniProtKB:P05480|ensembl:ENSMUSP00000090237 P Tyrosine-protein kinase SRC protein taxon:9031 20191214 Ensembl UniProtKB:A0A1I7Q3Z0
• WARNING - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- UniProtKB A0A1L1RR94 PSAP GO:0060736 GO_REF:0000104 IEA UniRule:UR000342797 P Prosaposin PSAP protein taxon:9031 20191214 UniProt UniProtKB:A0A1L1RR94
• WARNING - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- UniProtKB A0A1L1RR94 PSAP GO:0060742 GO_REF:0000104 IEA UniRule:UR000342797 P Prosaposin PSAP protein taxon:9031 20191214 UniProt UniProtKB:A0A1L1RR94
• WARNING - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- UniProtKB A0A3Q2UE42 PSEN1 GO:0021795 GO_REF:0000107 IEA UniProtKB:P49769|ensembl:ENSMUSP00000098786 P Presenilin PSEN1 protein taxon:9031 20191214 Ensembl UniProtKB:A0A3Q2UE42
• WARNING - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- UniProtKB A0A452J863 HOXA5 GO:0048286 GO_REF:0000107 IEA UniProtKB:P09021|ensembl:ENSMUSP00000039012 P Homeobox domain-containing protein HOXA5 protein taxon:9031 20191214 Ensembl UniProtKB:A0A452J863
• WARNING - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- UniProtKB E1BSP1 PSAP GO:0060736 PMID:21873635 IBA MGI:MGI:97783|PANTHER:PTN000159338 P Prosaposin PSAP protein taxon:9031 20170228 GO_Central UniProtKB:E1BSP1
• WARNING - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- UniProtKB E1BSP1 PSAP GO:0060742 PMID:21873635 IBA MGI:MGI:97783|PANTHER:PTN000159338 P Prosaposin PSAP protein taxon:9031 20170228 GO_Central UniProtKB:E1BSP1
• WARNING - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- UniProtKB F1NDM6 PCGF6 GO:0060819 PMID:21873635 IBA MGI:MGI:1916837|MGI:MGI:1923505|PANTHER:PTN000088533 P RING-type domain-containing protein PCGF6 protein taxon:9031 20180216 GO_Central UniProtKB:F1NDM6
• WARNING - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- UniProtKB F1NLA3 PCGF3 GO:0060819 PMID:21873635 IBA MGI:MGI:1916837|MGI:MGI:1923505|PANTHER:PTN000088533 P RING-type domain-containing protein PCGF3 protein taxon:9031 20180216 GO_Central UniProtKB:F1NLA3
• WARNING - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- UniProtKB O93345 Lef-1 GO:0021542 PMID:15642085 ISS UniProtKB:P27782 P HMG box domain-containing protein Lef-1|LEF-1|LEF1 protein taxon:9031 20130311 AgBase UniProtKB:O93345
• WARNING - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- UniProtKB O93345 Lef-1 GO:0021542 PMID:21873635 IBA MGI:MGI:96770|PANTHER:PTN000042972 P HMG box domain-containing protein Lef-1|LEF-1|LEF1 protein taxon:9031 20170228 GO_Central UniProtKB:O93345
• WARNING - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- UniProtKB O93345 Lef-1 GO:0021766 GO_REF:0000024 ISS UniProtKB:P27782 P HMG box domain-containing protein Lef-1|LEF-1|LEF1 protein taxon:9031 20100127 AgBase UniProtKB:O93345
• WARNING - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- UniProtKB O93345 Lef-1 GO:0021766 PMID:15642085 ISS UniProtKB:P27782 P HMG box domain-containing protein Lef-1|LEF-1|LEF1 protein taxon:9031 20130311 AgBase UniProtKB:O93345
• WARNING - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- UniProtKB O93345 Lef-1 GO:0030879 PMID:21873635 IBA MGI:MGI:96770|PANTHER:PTN000042972 P HMG box domain-containing protein Lef-1|LEF-1|LEF1 protein taxon:9031 20170228 GO_Central UniProtKB:O93345
• WARNING - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- UniProtKB O93345 Lef-1 GO:0060710 PMID:21873635 IBA MGI:MGI:96770|PANTHER:PTN000042973 P HMG box domain-containing protein Lef-1|LEF-1|LEF1 protein taxon:9031 20170228 GO_Central UniProtKB:O93345

gorule-0000015

Dual species taxon check

• total: 0

gorule-0000016

With/From: IC annotations require a With/From GO ID

• total: 0

gorule-0000017

IDA annotations must not have a With/From entry

• total: 0

gorule-0000018

IPI annotations require a With/From entry

• total: 0

gorule-0000027

Each identifier in GAF is valid

• total: 1

Messages

• WARNING - Invalid identifier: GORULE:0000027: assigned_by is not present in groups reference (HGNC-UCL) -- UniProtKB F1NYI8 LONP2 GO:0005782 GO_REF:0000024 ISS UniProtKB:Q6TXI3 C Lon protease homolog 2, peroxisomal LONP2 protein taxon:9031 20061204 HGNC-UCL UniProtKB:F1NYI8

gorule-0000028

Aspect can only be one of C, P, F and should be repaired using the GO term

• total: 0

gorule-0000029

All IEAs over a year old are removed

• total: 0

gorule-0000030

Deprecated GO_REFs are not allowed

• total: 0

gorule-0000037

IBA annotations should ONLY be assigned_by GO_Central and have PMID:21873635 as a reference

• total: 0

gorule-0000039

Protein complexes can not be annotated to GO:0032991 (protein-containing complex) or its descendants

• total: 0

gorule-0000042

Qualifier: IKR evidence code requires a NOT qualifier

• total: 0

gorule-0000043

Check for valid combination of evidence code and GO_REF

• total: 0

gorule-0000046

The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms.

• total: 38

Messages

• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB A0A1D5NXU2 FGFR2 GO:0042803 GO_REF:0000107 IEA UniProtKB:P21802|ensembl:ENSP00000410294 F Fibroblast growth factor receptor FGFR2 protein taxon:9031 20191214 Ensembl UniProtKB:A0A1D5NXU2
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB A0A1D5NZ26 TAF1B GO:0042803 GO_REF:0000107 IEA UniProtKB:Q9NZI5|ensembl:ENSP00000324693 F CP2 domain-containing protein TAF1B protein taxon:9031 20191214 Ensembl UniProtKB:A0A1D5NZ26
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB A0A1D5P127 KCNC4 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein KCNC4 protein taxon:9031 20191214 InterPro UniProtKB:A0A1D5P127
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB A0A1D5P3Y5 KCTD7 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein KCTD7 protein taxon:9031 20191214 InterPro UniProtKB:A0A1D5P3Y5
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB A0A1D5P723 TERF1 GO:0042803 GO_REF:0000002 IEA InterPro:IPR013867 F HTH myb-type domain-containing protein TERF1 protein taxon:9031 20191214 InterPro UniProtKB:A0A1D5P723
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB A0A1D5P8P4 KCND3 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein KCND3 protein taxon:9031 20191214 InterPro UniProtKB:A0A1D5P8P4
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB A0A1D5P9P3 ACTN1 GO:0042803 GO_REF:0000107 IEA UniProtKB:P12814|ensembl:ENSP00000377941 F Alpha-actinin-1 ACTN1 protein taxon:9031 20191214 Ensembl UniProtKB:A0A1D5P9P3
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB A0A1D5P9P3 ACTN1 GO:0042803 GO_REF:0000107 IEA UniProtKB:Q7TPR4|ensembl:ENSMUSP00000021554 F Alpha-actinin-1 ACTN1 protein taxon:9031 20191214 Ensembl UniProtKB:A0A1D5P9P3
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB A0A1D5PC94 HSF2 GO:0042803 PMID:9716376 IDA F HSF_DOMAIN domain-containing protein HSF2 protein taxon:9031 20170121 AgBase UniProtKB:A0A1D5PC94
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB A0A1D5PC94 HSF2 GO:0070207 PMID:9716376 IDA P HSF_DOMAIN domain-containing protein HSF2 protein taxon:9031 20170121 AgBase happens_during(GO:0010243),happens_during(GO:0014070) UniProtKB:A0A1D5PC94
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB A0A1D5PEQ3 KCTD17 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein KCTD17 protein taxon:9031 20191214 InterPro UniProtKB:A0A1D5PEQ3
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB A0A1D5PLW2 LDB1 GO:0042803 GO_REF:0000107 IEA UniProtKB:P70662|ensembl:ENSMUSP00000118546 F LID domain-containing protein LDB1 protein taxon:9031 20191214 Ensembl UniProtKB:A0A1D5PLW2
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB A0A1D5PLW2 LDB1 GO:0043621 GO_REF:0000107 IEA UniProtKB:P70662|ensembl:ENSMUSP00000118546 F LID domain-containing protein LDB1 protein taxon:9031 20191214 Ensembl UniProtKB:A0A1D5PLW2
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB A0A1D5PVF0 SIGMAR1 GO:0070207 GO_REF:0000107 IEA UniProtKB:Q99720|ensembl:ENSP00000277010 P Sigma non-opioid intracellular receptor 1 SIGMAR1 protein taxon:9031 20191214 Ensembl UniProtKB:A0A1D5PVF0
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB A0A1D5PY22 CRTC1 GO:0051289 GO_REF:0000002 IEA InterPro:IPR024783 P CREB regulated transcription coactivator 1 CRTC1 protein taxon:9031 20191214 InterPro UniProtKB:A0A1D5PY22
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB A0A1L1RMT7 CENPF GO:0042803 GO_REF:0000002 IEA InterPro:IPR019513 F Uncharacterized protein CENPF protein taxon:9031 20191214 InterPro UniProtKB:A0A1L1RMT7
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB A0A1L1RYG0 KCTD12 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein KCTD12 protein taxon:9031 20191214 InterPro UniProtKB:A0A1L1RYG0
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB A0A3Q2TTK5 KCNC2 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein KCNC2 protein taxon:9031 20191214 InterPro UniProtKB:A0A3Q2TTK5
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB A0A3Q2TTX5 LOC100859454 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein LOC100859454 protein taxon:9031 20191214 InterPro UniProtKB:A0A3Q2TTX5
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB A0A3Q2TX12 GPD1L2 GO:0042803 GO_REF:0000002 IEA InterPro:IPR017751 F Glycerol-3-phosphate dehydrogenase [NAD(+)] GPD1L2 protein taxon:9031 20191214 InterPro UniProtKB:A0A3Q2TX12
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB A0A3Q2TY64 LOC100859454 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein LOC100859454 protein taxon:9031 20191214 InterPro UniProtKB:A0A3Q2TY64
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB A0A3Q2U1G0 GSS GO:0042803 GO_REF:0000104 IEA UniRule:UR000131768 F Glutathione synthetase GSS protein taxon:9031 20191214 UniProt UniProtKB:A0A3Q2U1G0
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB A0A3Q2U986 KCNB2 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein KCNB2 protein taxon:9031 20191214 InterPro UniProtKB:A0A3Q2U986
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB A0A3Q2UBY8 CENPF GO:0042803 GO_REF:0000002 IEA InterPro:IPR019513 F Uncharacterized protein CENPF protein taxon:9031 20191214 InterPro UniProtKB:A0A3Q2UBY8
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB A0A3Q2UFI1 SLC39A13 GO:0042803 GO_REF:0000107 IEA UniProtKB:Q96H72|ensembl:ENSP00000354689 F Zinc transporter ZIP13 SLC39A13 protein taxon:9031 20191214 Ensembl UniProtKB:A0A3Q2UFI1
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB A0A3Q2UHS1 JAM3 GO:0042803 GO_REF:0000002 IEA InterPro:IPR042974 F Junctional adhesion molecule 3 JAM3 protein taxon:9031 20191214 InterPro UniProtKB:A0A3Q2UHS1
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB A0A3Q2UJ47 KCNC2 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein KCNC2 protein taxon:9031 20191214 InterPro UniProtKB:A0A3Q2UJ47
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB A0A3Q3ADB2 NECTIN3 GO:0042803 GO_REF:0000002 IEA InterPro:IPR033319 F Nectin cell adhesion molecule 3 NECTIN3 protein taxon:9031 20191214 InterPro UniProtKB:A0A3Q3ADB2
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB A0A3Q3AJJ9 NECTIN1 GO:0042803 GO_REF:0000002 IEA InterPro:IPR033314 F Nectin cell adhesion molecule 1 NECTIN1 protein taxon:9031 20191214 InterPro UniProtKB:A0A3Q3AJJ9
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB A0A3Q3AY63 LOC100859454 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein LOC100859454 protein taxon:9031 20191214 InterPro UniProtKB:A0A3Q3AY63
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB A0A452J7Q5 TNNC1 GO:0042803 GO_REF:0000107 IEA UniProtKB:P63316|ensembl:ENSP00000232975 F Troponin C, slow skeletal and cardiac muscles TNNC1 protein taxon:9031 20191214 Ensembl UniProtKB:A0A452J7Q5
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB A0A452J823 PTGS2 GO:0042803 GO_REF:0000107 IEA UniProtKB:Q05769|ensembl:ENSMUSP00000035065 F EGF-like domain-containing protein PTGS2 protein taxon:9031 20191214 Ensembl UniProtKB:A0A452J823
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB F1NBQ3 KCNC2 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein KCNC2 protein taxon:9031 20191214 InterPro UniProtKB:F1NBQ3
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB F1NJZ8 KCTD1 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein KCTD1 protein taxon:9031 20191214 InterPro UniProtKB:F1NJZ8
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB F1NSB3 JAM3 GO:0042803 GO_REF:0000002 IEA InterPro:IPR042974 F Junctional adhesion molecule 3 JAM3 protein taxon:9031 20191214 InterPro UniProtKB:F1NSB3
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB K4HVD3 KCTD15 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein KCTD15 protein taxon:9031 20191214 InterPro UniProtKB:K4HVD3
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB P05094 ACTN1 GO:0042803 PMID:8037676 IDA F Alpha-actinin-1 ACTN1 protein taxon:9031 20150407 AgBase UniProtKB:P05094-2
• WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- UniProtKB Q90979 IBR GO:0042803 PMID:8524232 IDA F Transcription factor IBR|F|NRF1 protein taxon:9031 20150422 AgBase UniProtKB:Q90979

gorule-0000050

Annotations to ISS, ISA and ISO should not be self-referential

• total: 0

other

• total: 1

Messages

• ERROR - Syntax error in annotation extension field: does not follow REL(ID) syntax (CL:0000057) -- UniProtKB F1NJT3 FN1 GO:0008283 PMID:6178746 IDA P Fibronectin FN1 protein taxon:9031 20191105 AgBase CL:0000057 UniProtKB:F1NJT3

#Line number RuleID ViolationType Message Line
#------------
#------------
# Validation for #22966 annotations in 22985 lines
#------------
#Line number RuleID ViolationType Message Line
#------------
# GO_AR:0000014 Valid GO term ID Error count: 2
1424 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB A0A1D5P1B0 CLASP2 GO:0010717 PMID:23940118 IMP P Uncharacterized protein CLASP2 protein taxon:9031 20170214 UniProt happens_during(GO:0007369),has_agent(GO:0043256),occurs_in(CL:0000352) UniProtKB:A0A1D5P1B0
1426 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB A0A1D5P1B0 CLASP2 GO:1904261 PMID:23940118 IMP P Uncharacterized protein CLASP2 protein taxon:9031 20170214 UniProt happens_during(GO:0001837),happens_during(GO:0007369),has_agent(GO:0043256),occurs_in(CL:0000352) UniProtKB:A0A1D5P1B0
#------------
# GO_AR:0000008 No annotations should be made to uninformative high level terms Warning count: 3
3606 GO_AR:0000008 Warning Do not annotate to: GO:0005622 'intracellular' The term is considered to high level, as marked via the subset tag: gocheck_do_not_annotate UniProtKB A0A1D5PFN2 PALM GO:0005622 PMID:9813098 IDA C Paralemmin-1 PALM protein taxon:9031 20170202 AgBase part_of(UBERON:0000955) UniProtKB:A0A1D5PFN2
22676 GO_AR:0000008 Warning Do not annotate to: GO:0005622 'intracellular' The term is considered to high level, as marked via the subset tag: gocheck_do_not_annotate UniProtKB Q9YGL6 PALM GO:0005622 PMID:9813098 IDA C Paralemmin-1 PALM protein taxon:9031 20170202 AgBase part_of(UBERON:0000955) UniProtKB:Q9YGL6-2
22677 GO_AR:0000008 Warning Do not annotate to: GO:0005622 'intracellular' The term is considered to high level, as marked via the subset tag: gocheck_do_not_annotate UniProtKB Q9YGL6 PALM GO:0005622 PMID:9813098 IDA C Paralemmin-1 PALM protein taxon:9031 20170202 AgBase part_of(UBERON:0000955) UniProtKB:Q9YGL6-3
#------------

GO:0005829 cytosol AnnotationPropagation C GO:0042147 retrograde transport, endosome to Golgi ISS
GO:0006259 DNA metabolic process AnnotationPropagation P GO:0004531 deoxyribonuclease II activity IDA
GO:0090305 nucleic acid phosphodiester bond hydrolysis AnnotationPropagation P GO:0004531 deoxyribonuclease II activity IDA
GO:0008144 drug binding FoldBasedPredictor GO:1990239 steroid hormone binding has_input CHEBI:17026 progesterone occurs_in UBERON:0000993 oviduct ISS
GO:0072348 sulfur compound transport FoldBasedPredictor GO:0055085 transmembrane transport transports_or_maintains_localization_of CHEBI:8927 S-(2,4-dinitrophenyl)glutathione ISS
GO:0071705 nitrogen compound transport FoldBasedPredictor GO:0055085 transmembrane transport transports_or_maintains_localization_of CHEBI:8927 S-(2,4-dinitrophenyl)glutathione ISS
GO:0015711 organic anion transport FoldBasedPredictor GO:0055085 transmembrane transport transports_or_maintains_localization_of CHEBI:8927 S-(2,4-dinitrophenyl)glutathione ISS
GO:0098656 anion transmembrane transport FoldBasedPredictor GO:0055085 transmembrane transport transports_or_maintains_localization_of CHEBI:8927 S-(2,4-dinitrophenyl)glutathione ISS
GO:0044295 axonal growth cone FoldBasedPredictor GO:2000009 negative regulation of protein localization to cell surface occurs_in GO:0044295 axonal growth cone transports_or_maintains_localization_of UniProtKB:P79795 IMP
GO:0005829 cytosol FoldBasedPredictor GO:0031072 heat shock protein binding occurs_in GO:0005829 cytosol occurs_in UBERON:0000993 oviduct IPI