GAF summary
Found 22974 annotations in 22993 lines.
GAF Validation Summary Errors are reported first.
For rule GO_AR:0000014 (http://www.geneontology.org/GO.annotation_qc.shtml#GO_AR:0000014) Valid GO term ID, there are 2 violations with type Error.
For rule GO_AR:0000008 (http://www.geneontology.org/GO.annotation_qc.shtml#GO_AR:0000008) No annotations should be made to uninformative high level terms, there are 3 violations with type Warning.
For rule GO_AR:0000014 (http://www.geneontology.org/GO.annotation_qc.shtml#GO_AR:0000014) Valid GO term ID, there are 3 violations with type Warning.
GAF Prediction Summary
Found 10 predictions, see prediction file for details.
Used Ontology Summary
go/extensions/go-gaf go/releases/2019-10-31/extensions/go-gaf.owl
This report generated on 2019-11-02
!gaf-version: 2.1
!
!The set of protein accessions included in this file is based on UniProt complete proteomes, which may provide more than one protein per gene.
!They include all Swiss-Prot entries for the species plus any TrEMBL entries that have an Ensembl DR line. The TrEMBL entries are likely to overlap with the Swiss-Prot entries or their isoforms.
!If a particular protein accession is not annotated with GO, then it will not appear in this file.
!
!Note that the annotation set in this file is filtered in order to reduce redundancy; the full, unfiltered set can be found in
!ftp://ftp.ebi.ac.uk/pub/databases/GO/goa/UNIPROT/goa_uniprot_all.gaf.gz
!
!Generated: 2019-10-15 18:53
!GO-version: http://purl.obolibrary.org/obo/go/releases/2019-10-03/extensions/go-plus.owl
!
No 'NOT' annotations to 'protein binding ; GO:0005515'
IEP and HEP usage is restricted to terms from the Biological Process ontology
IPI should not be used with catalytic activity molecular function terms
No annotations should be made to uninformative high level terms
UniProtKB A0A1D5PFN2 PALM GO:0005622 PMID:9813098 IDA C Paralemmin-1 PALM protein taxon:9031 20170202 AgBase part_of(UBERON:0000955) UniProtKB:A0A1D5PFN2
UniProtKB Q9YGL6 PALM GO:0005622 PMID:9813098 IDA C Paralemmin-1 PALM protein taxon:9031 20170202 AgBase part_of(UBERON:0000955) UniProtKB:Q9YGL6-2
UniProtKB Q9YGL6 PALM GO:0005622 PMID:9813098 IDA C Paralemmin-1 PALM protein taxon:9031 20170202 AgBase part_of(UBERON:0000955) UniProtKB:Q9YGL6-3
ND annotations to root nodes only; and only root nodes can have the evidence code ND.
Taxon-appropriate annotation check
Dual species taxon check
With/From: IC annotations require a With/From GO ID
IDA annotations must not have a With/From entry
IPI annotations require a With/From entry
Automatic repair of annotations to merged or obsoleted terms
UniProtKB A0A3Q2UH30 A0A3Q2UH30 GO:0000980 GO_REF:0000107 IEA UniProtKB:P25208|ensembl:ENSP00000240055 F CBFD_NFYB_HMF domain-containing protein protein taxon:9031 20190925 Ensembl UniProtKB:A0A3Q2UH30
UniProtKB H9L378 NFE2L1 GO:0000980 GO_REF:0000107 IEA UniProtKB:Q61985|ensembl:ENSMUSP00000080467 F BZIP domain-containing protein NFE2L1 protein taxon:9031 20190925 Ensembl UniProtKB:H9L378
Each identifier in GAF is valid
UniProtKB F1NYI8 LONP2 GO:0005782 GO_REF:0000024 ISS UniProtKB:Q6TXI3 C Lon protease homolog 2, peroxisomal LONP2 protein taxon:9031 20061204 HGNC-UCL UniProtKB:F1NYI8
Aspect can only be one of C, P, F and should be repaired using the GO term
All IEAs over a year old are removed
Deprecated GO_REFs are not allowed
Public Reference IDs (PMID, PMC, doi, or GO_REF) should be preferred over group specific Reference IDs
UniProtKB E1C8M4 PIK3R1 GO:0005829 Reactome:R-GGA-9607044 TAS C Uncharacterized protein PIK3R1 protein taxon:9031 20180430 Reactome UniProtKB:E1C8M4
UniProtKB F1P587 C4A GO:0005576 Reactome:R-GGA-2132085 TAS C Anaphylatoxin-like domain-containing protein C4A protein taxon:9031 20120221 Reactome UniProtKB:F1P587
UniProtKB F1P587 C4A GO:0005576 Reactome:R-GGA-2132222 TAS C Anaphylatoxin-like domain-containing protein C4A protein taxon:9031 20120221 Reactome UniProtKB:F1P587
UniProtKB F1P587 C4A GO:0005576 Reactome:R-GGA-2132233 TAS C Anaphylatoxin-like domain-containing protein C4A protein taxon:9031 20120221 Reactome UniProtKB:F1P587
UniProtKB F1P587 C4A GO:0005576 Reactome:R-GGA-2530584 TAS C Anaphylatoxin-like domain-containing protein C4A protein taxon:9031 20120221 Reactome UniProtKB:F1P587
UniProtKB F1P587 C4A GO:0006956 Reactome:R-GGA-2132285 TAS P Anaphylatoxin-like domain-containing protein C4A protein taxon:9031 20180419 Reactome UniProtKB:F1P587
UniProtKB F1P587 C4A GO:0030449 Reactome:R-GGA-2132281 TAS P Anaphylatoxin-like domain-containing protein C4A protein taxon:9031 20140218 Reactome UniProtKB:F1P587
UniProtKB Q6Q1Q7 MASP2 GO:0001867 Reactome:R-GGA-2132270 TAS P CUB domain-containing protein MASP2 protein taxon:9031 20140218 Reactome UniProtKB:Q6Q1Q7
UniProtKB Q6Q1Q7 MASP2 GO:0005576 Reactome:R-GGA-2132187 TAS C CUB domain-containing protein MASP2 protein taxon:9031 20120221 Reactome UniProtKB:Q6Q1Q7
UniProtKB Q6Q1Q7 MASP2 GO:0005576 Reactome:R-GGA-2132206 TAS C CUB domain-containing protein MASP2 protein taxon:9031 20130205 Reactome UniProtKB:Q6Q1Q7
UniProtKB Q6Q1Q7 MASP2 GO:0005576 Reactome:R-GGA-2132222 TAS C CUB domain-containing protein MASP2 protein taxon:9031 20130205 Reactome UniProtKB:Q6Q1Q7
UniProtKB Q6Q1Q7 MASP2 GO:0005576 Reactome:R-GGA-2132233 TAS C CUB domain-containing protein MASP2 protein taxon:9031 20130205 Reactome UniProtKB:Q6Q1Q7
UniProtKB Q6Q1Q7 MASP2 GO:0006956 Reactome:R-GGA-2132263 TAS P CUB domain-containing protein MASP2 protein taxon:9031 20140218 Reactome UniProtKB:Q6Q1Q7
IBA annotations should ONLY be assigned_by GO_Central and have PMID:21873635 as a reference
Protein complexes can not be annotated to GO:0032991 (protein-containing complex) or its descendants
Qualifier: IKR evidence code requires a NOT qualifier
Check for valid combination of evidence code and GO_REF
The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms.
UniProtKB A0A1D5NXU2 FGFR2 GO:0042803 GO_REF:0000107 IEA UniProtKB:P21802|ensembl:ENSP00000410294 F Fibroblast growth factor receptor FGFR2 protein taxon:9031 20190925 Ensembl UniProtKB:A0A1D5NXU2
UniProtKB A0A1D5NZ26 TAF1B GO:0042803 GO_REF:0000107 IEA UniProtKB:Q9NZI5|ensembl:ENSP00000324693 F CP2 domain-containing protein TAF1B protein taxon:9031 20190925 Ensembl UniProtKB:A0A1D5NZ26
UniProtKB A0A1D5P127 KCNC4 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein KCNC4 protein taxon:9031 20191012 InterPro UniProtKB:A0A1D5P127
UniProtKB A0A1D5P3Y5 KCTD7 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein KCTD7 protein taxon:9031 20191012 InterPro UniProtKB:A0A1D5P3Y5
UniProtKB A0A1D5P723 TERF1 GO:0042803 GO_REF:0000002 IEA InterPro:IPR013867 F HTH myb-type domain-containing protein TERF1 protein taxon:9031 20191012 InterPro UniProtKB:A0A1D5P723
UniProtKB A0A1D5P8P4 KCND1 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein KCND1 protein taxon:9031 20191012 InterPro UniProtKB:A0A1D5P8P4
UniProtKB A0A1D5P9P3 ACTN1 GO:0042803 GO_REF:0000107 IEA UniProtKB:P12814|ensembl:ENSP00000377941 F Alpha-actinin-1 ACTN1 protein taxon:9031 20190925 Ensembl UniProtKB:A0A1D5P9P3
UniProtKB A0A1D5P9P3 ACTN1 GO:0042803 GO_REF:0000107 IEA UniProtKB:Q7TPR4|ensembl:ENSMUSP00000021554 F Alpha-actinin-1 ACTN1 protein taxon:9031 20190925 Ensembl UniProtKB:A0A1D5P9P3
UniProtKB A0A1D5PC94 HSF2 GO:0042803 PMID:9716376 IDA F HSF_DOMAIN domain-containing protein HSF2 protein taxon:9031 20170121 AgBase UniProtKB:A0A1D5PC94
UniProtKB A0A1D5PC94 HSF2 GO:0070207 PMID:9716376 IDA P HSF_DOMAIN domain-containing protein HSF2 protein taxon:9031 20170121 AgBase happens_during(GO:0010243),happens_during(GO:0014070) UniProtKB:A0A1D5PC94
UniProtKB A0A1D5PEQ3 KCTD17 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein KCTD17 protein taxon:9031 20191012 InterPro UniProtKB:A0A1D5PEQ3
UniProtKB A0A1D5PLW2 LDB1 GO:0042803 GO_REF:0000107 IEA UniProtKB:P70662|ensembl:ENSMUSP00000118546 F LID domain-containing protein LDB1 protein taxon:9031 20190925 Ensembl UniProtKB:A0A1D5PLW2
UniProtKB A0A1D5PLW2 LDB1 GO:0043621 GO_REF:0000107 IEA UniProtKB:P70662|ensembl:ENSMUSP00000118546 F LID domain-containing protein LDB1 protein taxon:9031 20190925 Ensembl UniProtKB:A0A1D5PLW2
UniProtKB A0A1D5PNV5 ACTN2 GO:0042803 GO_REF:0000107 IEA UniProtKB:P35609|ensembl:ENSP00000355537 F Alpha-actinin-2 ACTN2 protein taxon:9031 20190925 Ensembl UniProtKB:A0A1D5PNV5
UniProtKB A0A1D5PNV5 ACTN2 GO:0051289 GO_REF:0000107 IEA UniProtKB:P35609|ensembl:ENSP00000355537 P Alpha-actinin-2 ACTN2 protein taxon:9031 20190925 Ensembl UniProtKB:A0A1D5PNV5
UniProtKB A0A1D5PVF0 SIGMAR1 GO:0070207 GO_REF:0000107 IEA UniProtKB:Q99720|ensembl:ENSP00000277010 P Sigma non-opioid intracellular receptor 1 SIGMAR1 protein taxon:9031 20190925 Ensembl UniProtKB:A0A1D5PVF0
UniProtKB A0A1D5PY22 CRTC1 GO:0051289 GO_REF:0000002 IEA InterPro:IPR024783 P Uncharacterized protein CRTC1 protein taxon:9031 20191012 InterPro UniProtKB:A0A1D5PY22
UniProtKB A0A1L1RMT7 CENPF GO:0042803 GO_REF:0000002 IEA InterPro:IPR019513 F Uncharacterized protein CENPF protein taxon:9031 20191012 InterPro UniProtKB:A0A1L1RMT7
UniProtKB A0A1L1RYG0 KCTD12 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein KCTD12 protein taxon:9031 20191012 InterPro UniProtKB:A0A1L1RYG0
UniProtKB A0A3Q2TTK5 KCNC2 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein KCNC2 protein taxon:9031 20191012 InterPro UniProtKB:A0A3Q2TTK5
UniProtKB A0A3Q2TTX5 LOC100859454 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein LOC100859454 protein taxon:9031 20191012 InterPro UniProtKB:A0A3Q2TTX5
UniProtKB A0A3Q2TX12 GPD1L2 GO:0042803 GO_REF:0000002 IEA InterPro:IPR017751 F Glycerol-3-phosphate dehydrogenase [NAD(+)] GPD1L2 protein taxon:9031 20191012 InterPro UniProtKB:A0A3Q2TX12
UniProtKB A0A3Q2TY64 LOC100859454 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein LOC100859454 protein taxon:9031 20191012 InterPro UniProtKB:A0A3Q2TY64
UniProtKB A0A3Q2U1G0 GSS GO:0042803 GO_REF:0000104 IEA UniRule:UR000131768 F Glutathione synthetase GSS protein taxon:9031 20191012 UniProt UniProtKB:A0A3Q2U1G0
UniProtKB A0A3Q2U986 KCNB2 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein KCNB2 protein taxon:9031 20191012 InterPro UniProtKB:A0A3Q2U986
UniProtKB A0A3Q2UBY8 CENPF GO:0042803 GO_REF:0000002 IEA InterPro:IPR019513 F Uncharacterized protein CENPF protein taxon:9031 20191012 InterPro UniProtKB:A0A3Q2UBY8
UniProtKB A0A3Q2UF90 CARS GO:0042803 GO_REF:0000107 IEA UniProtKB:P49589|ensembl:ENSP00000369897 F tRNA-synt_1e domain-containing protein CARS protein taxon:9031 20190925 Ensembl UniProtKB:A0A3Q2UF90
UniProtKB A0A3Q2UFI1 SLC39A13 GO:0042803 GO_REF:0000107 IEA UniProtKB:Q96H72|ensembl:ENSP00000354689 F Zinc transporter ZIP13 SLC39A13 protein taxon:9031 20190925 Ensembl UniProtKB:A0A3Q2UFI1
UniProtKB A0A3Q2UHS1 JAM3 GO:0042803 GO_REF:0000002 IEA InterPro:IPR042974 F Uncharacterized protein JAM3 protein taxon:9031 20191012 InterPro UniProtKB:A0A3Q2UHS1
UniProtKB A0A3Q2UJ47 KCNC2 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein KCNC2 protein taxon:9031 20191012 InterPro UniProtKB:A0A3Q2UJ47
UniProtKB A0A3Q3ADB2 NECTIN3 GO:0042803 GO_REF:0000002 IEA InterPro:IPR033319 F Uncharacterized protein NECTIN3 protein taxon:9031 20191012 InterPro UniProtKB:A0A3Q3ADB2
UniProtKB A0A3Q3AJJ9 NECTIN1 GO:0042803 GO_REF:0000002 IEA InterPro:IPR033314 F Uncharacterized protein NECTIN1 protein taxon:9031 20191012 InterPro UniProtKB:A0A3Q3AJJ9
UniProtKB A0A3Q3AY63 LOC100859454 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein LOC100859454 protein taxon:9031 20191012 InterPro UniProtKB:A0A3Q3AY63
UniProtKB A0A452J7Q5 TNNC1 GO:0042803 GO_REF:0000107 IEA UniProtKB:P63316|ensembl:ENSP00000232975 F Troponin C, slow skeletal and cardiac muscles TNNC1 protein taxon:9031 20190925 Ensembl UniProtKB:A0A452J7Q5
UniProtKB A0A452J823 PTGS2 GO:0042803 GO_REF:0000107 IEA UniProtKB:Q05769|ensembl:ENSMUSP00000035065 F EGF-like domain-containing protein PTGS2 protein taxon:9031 20190925 Ensembl UniProtKB:A0A452J823
UniProtKB F1NBQ3 KCNC2 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein KCNC2 protein taxon:9031 20191012 InterPro UniProtKB:F1NBQ3
UniProtKB F1NJZ8 KCTD1 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein KCTD1 protein taxon:9031 20191012 InterPro UniProtKB:F1NJZ8
UniProtKB F1NSB3 JAM3 GO:0042803 GO_REF:0000002 IEA InterPro:IPR042974 F Uncharacterized protein JAM3 protein taxon:9031 20191012 InterPro UniProtKB:F1NSB3
UniProtKB K4HVD3 KCTD15 GO:0051260 GO_REF:0000002 IEA InterPro:IPR003131 P BTB domain-containing protein KCTD15 protein taxon:9031 20191012 InterPro UniProtKB:K4HVD3
UniProtKB P05094 ACTN1 GO:0042803 PMID:8037676 IDA F Alpha-actinin-1 ACTN1 protein taxon:9031 20150407 AgBase UniProtKB:P05094-2
UniProtKB Q90979 IBR GO:0042803 PMID:8524232 IDA F Transcription factor IBR|F|NRF1 protein taxon:9031 20150422 AgBase UniProtKB:Q90979
Annotations to ISS, ISA and ISO should not be self-referential