GAF summary
Found 142014 annotations in 142033 lines.
GAF Validation Summary Errors are reported first.
For rule GO_AR:0000005 (http://www.geneontology.org/GO.annotation_qc.shtml#GO_AR:0000005) No ISS or ISS-related annotations to 'protein binding ; GO:0005515', there are 2 violations with type Error.
For rule GO_AR:0000003 (http://www.geneontology.org/GO.annotation_qc.shtml#GO_AR:0000003) Annotations to 'binding ; GO:0005488' and 'protein binding ; GO:0005515' should be made with IPI and an interactor in the 'with' field, there are 2 violations with type Warning.
For rule GO_AR:0000008 (http://www.geneontology.org/GO.annotation_qc.shtml#GO_AR:0000008) No annotations should be made to uninformative high level terms, there are 2 violations with type Warning.
GAF Prediction Summary
Found 25 predictions, see prediction file for details.
Used Ontology Summary
go/extensions/go-gaf go/releases/2019-06-28/extensions/go-gaf.owl
This report generated on 2019-07-01
!gaf-version: 2.1
!
!The set of protein accessions included in this file is based on UniProt reference proteomes, which provide one protein per gene.
!They include the protein sequences annotated in Swiss-Prot or the longest TrEMBL transcript if there is no Swiss-Prot record.
!If a particular protein accession is not annotated with GO, then it will not appear in this file.
!
!Note that the annotation set in this file is filtered in order to reduce redundancy; the full, unfiltered set can be found in
!ftp://ftp.ebi.ac.uk/pub/databases/GO/goa/UNIPROT/goa_uniprot_all.gz
!
!Generated: 2019-06-03 16:53
!GO-version: http://purl.obolibrary.org/obo/go/releases/2019-06-02/extensions/go-plus.owl
!
No annotations should be made to uninformative high level terms
UniProtKB F1RIT1 TRPV4 GO:0005622 PMID:19790068 IDA C Transient receptor potential cation channel subfamily V member 4 isoform X1 TRPV4 protein taxon:9823 20150803 AgBase part_of(CL:0000138)
UniProtKB Q4PLW0 PLIN2 GO:0005622 PMID:21420243 IDA C Perilipin-2 PLIN2|ADFP|ADRP protein taxon:9823 20150513 AgBase part_of(CL:0000187),part_of(UBERON:0001381)
Automatic repair of annotations to merged or obsoleted terms
UniProtKB A0A140TAK4 MYD88 GO:0044130 GO_REF:0000107 IEA UniProtKB:P22366|ensembl:ENSMUSP00000035092 P Myeloid differentiation primary response protein MyD88 MYD88 protein taxon:9823 20190601 Ensembl
UniProtKB A0A286ZTB8 ITGB1BP1 GO:0050880 GO_REF:0000107 IEA UniProtKB:O14713|ensembl:ENSP00000353850 P Uncharacterized protein ITGB1BP1 protein taxon:9823 20190601 Ensembl
UniProtKB A0A286ZTP3 FOXC1 GO:0050880 GO_REF:0000107 IEA UniProtKB:Q61572|ensembl:ENSMUSP00000052196 P Uncharacterized protein FOXC1 protein taxon:9823 20190601 Ensembl
UniProtKB A0A287AA47 GCLM GO:0050880 GO_REF:0000107 IEA UniProtKB:P48507|ensembl:ENSP00000359258 P Glutamate--cysteine ligase regulatory subunit GCLM protein taxon:9823 20190601 Ensembl
UniProtKB A0A287AFQ6 FOXC2 GO:0050880 GO_REF:0000107 IEA UniProtKB:Q61850|ensembl:ENSMUSP00000055290 P Uncharacterized protein FOXC2 protein taxon:9823 20190601 Ensembl
UniProtKB A0A287AKB2 YOD1 GO:1904265 GO_REF:0000002 IEA InterPro:IPR039138 F Ubiquitin thioesterase OTU1 isoform 1 YOD1 protein taxon:9823 20190601 InterPro
UniProtKB A0A287AKR3 DICER1 GO:0035068 GO_REF:0000107 IEA UniProtKB:Q9UPY3|ensembl:ENSP00000437256 C Uncharacterized protein DICER1 protein taxon:9823 20190601 Ensembl
UniProtKB A0A287AXM6 NOS3 GO:0050880 GO_REF:0000107 IEA UniProtKB:P70313|ensembl:ENSMUSP00000030834 P Nitric oxide synthase NOS3 protein taxon:9823 20190601 Ensembl
UniProtKB A0A287B559 TARBP2 GO:0035068 GO_REF:0000107 IEA UniProtKB:P97473|ensembl:ENSMUSP00000023813 C RISC-loading complex subunit TARBP2 TARBP2 protein taxon:9823 20190601 Ensembl
UniProtKB A0A287B559 TARBP2 GO:0035068 GO_REF:0000107 IEA UniProtKB:Q15633|ensembl:ENSP00000266987 C RISC-loading complex subunit TARBP2 TARBP2 protein taxon:9823 20190601 Ensembl
UniProtKB A0A287B5S7 AGO2 GO:0035068 GO_REF:0000104 IEA UniRule:UR000107560 C Protein argonaute-2 AGO2|EIF2C2 protein taxon:9823 20190601 UniProt
UniProtKB A0A287B5Y6 LBP GO:0044130 GO_REF:0000107 IEA UniProtKB:Q61805|ensembl:ENSMUSP00000016168 P Lipopolysaccharide-binding protein LBP protein taxon:9823 20190601 Ensembl
UniProtKB A0A287B827 MBL2 GO:0044130 GO_REF:0000107 IEA UniProtKB:P11226|ensembl:ENSP00000363079 P Mannose-binding protein C MBL2 protein taxon:9823 20190601 Ensembl
UniProtKB A0A287B827 MBL2 GO:0044130 GO_REF:0000107 IEA UniProtKB:P41317|ensembl:ENSMUSP00000025797 P Mannose-binding protein C MBL2 protein taxon:9823 20190601 Ensembl
UniProtKB A0A287BDE2 GCLC GO:0050880 GO_REF:0000107 IEA UniProtKB:P48506|ensembl:ENSP00000497574 P Uncharacterized protein GCLC protein taxon:9823 20190601 Ensembl
UniProtKB A0A287BE94 TNRC6A GO:0035068 GO_REF:0000107 IEA UniProtKB:Q8NDV7|ensembl:ENSP00000379144 C Uncharacterized protein TNRC6A protein taxon:9823 20190601 Ensembl
UniProtKB A5A752 EDN3 GO:0050880 GO_REF:0000037 IEA UniProtKB-KW:KW-0838 P Endothelin-3 EDN3 protein taxon:9823 20190601 UniProt
UniProtKB F1RF79 NPPA GO:0050880 GO_REF:0000038 IEA UniProtKB-KW:KW-0838 P Natriuretic peptides A NPPA protein taxon:9823 20190601 UniProt
UniProtKB F1RMJ9 OSBP GO:0044128 GO_REF:0000107 IEA UniProtKB:P22059|ensembl:ENSP00000263847 P Oxysterol-binding protein OSBP protein taxon:9823 20190601 Ensembl
UniProtKB F1RRJ4 XPO5 GO:0035068 GO_REF:0000107 IEA UniProtKB:Q9HAV4|ensembl:ENSP00000265351 C Uncharacterized protein XPO5 protein taxon:9823 20190601 Ensembl
UniProtKB F1S445 SQSTM1 GO:0044130 GO_REF:0000107 IEA UniProtKB:Q64337|ensembl:ENSMUSP00000099835 P Uncharacterized protein SQSTM1 protein taxon:9823 20190601 Ensembl
UniProtKB I3L5V9 AGO3 GO:0035068 GO_REF:0000104 IEA UniRule:UR000107558 C Protein argonaute-3 AGO3|EIF2C3 protein taxon:9823 20190601 UniProt
UniProtKB I3LK80 ELANE GO:0044130 GO_REF:0000107 IEA UniProtKB:Q3UP87|ensembl:ENSMUSP00000038925 P Uncharacterized protein ELANE protein taxon:9823 20190601 Ensembl
UniProtKB I3LMQ0 LOC100511343 GO:0044130 GO_REF:0000107 IEA UniProtKB:Q08857|ensembl:ENSMUSP00000133008 P Uncharacterized protein LOC100511343 protein taxon:9823 20190601 Ensembl
UniProtKB K7GND3 DHX9 GO:0035068 GO_REF:0000107 IEA UniProtKB:Q08211|ensembl:ENSP00000356520 C ATP-dependent RNA helicase A DHX9 protein taxon:9823 20190601 Ensembl
UniProtKB K7GRV6 MPO GO:0044130 GO_REF:0000107 IEA UniProtKB:P11247|ensembl:ENSMUSP00000020779 P Uncharacterized protein MPO protein taxon:9823 20190601 Ensembl
UniProtKB P01183 AVP GO:0050880 GO_REF:0000037 IEA UniProtKB-KW:KW-0838 P Vasopressin-neurophysin 2-copeptin AVP protein taxon:9823 20190601 UniProt
UniProtKB P07634 NPPB GO:0050880 GO_REF:0000037 IEA UniProtKB-KW:KW-0838 P Natriuretic peptides B NPPB protein taxon:9823 20190601 UniProt
UniProtKB P09558 EDN1 GO:0050880 GO_REF:0000037 IEA UniProtKB-KW:KW-0838 P Endothelin-1 EDN1 protein taxon:9823 20190601 UniProt
UniProtKB P18104 NPPC GO:0050880 GO_REF:0000037 IEA UniProtKB-KW:KW-0838 P C-type natriuretic peptide NPPC|CNP protein taxon:9823 20190601 UniProt
UniProtKB P23563 TNF GO:0044130 GO_REF:0000107 IEA UniProtKB:P06804|ensembl:ENSMUSP00000025263 P Tumor necrosis factor TNF|TNFA|TNFSF2 protein taxon:9823 20190601 Ensembl
UniProtKB P24259 NPPA GO:0050880 GO_REF:0000037 IEA UniProtKB-KW:KW-0838 P Natriuretic peptides A NPPA protein taxon:9823 20190601 UniProt
UniProtKB P26445 LTA GO:0044130 GO_REF:0000107 IEA UniProtKB:P09225|ensembl:ENSMUSP00000025266 P Lymphotoxin-alpha LTA|TNFB|TNFSF1 protein taxon:9823 20190601 Ensembl
UniProtKB Q28938 IL12B GO:0044130 GO_REF:0000107 IEA UniProtKB:P43432|ensembl:ENSMUSP00000125867 P Interleukin-12 subunit beta IL12B protein taxon:9823 20190601 Ensembl
UniProtKB Q29055 IL10 GO:0044130 GO_REF:0000107 IEA UniProtKB:P18893|ensembl:ENSMUSP00000016673 P Interleukin-10 IL10 protein taxon:9823 20190601 Ensembl
UniProtKB Q5U9S1 MBL1 GO:0044130 GO_REF:0000107 IEA UniProtKB:P39039|ensembl:ENSMUSP00000153147 P Mannose-binding protein A MBL1|MBL-A protein taxon:9823 20190601 Ensembl
UniProtKB Q6T5D3 IRF8 GO:0044130 GO_REF:0000107 IEA UniProtKB:P23611|ensembl:ENSMUSP00000040245 P Interferon regulatory factor 8 IRF8 protein taxon:9823 20190601 Ensembl
UniProtKB Q85ZW4 SLA-DRA1 GO:0002506 GO_REF:0000107 IEA UniProtKB:P01903|ensembl:ENSP00000378786 P MHC class II antigen SLA-DRA1|DRA|HLA-DRA|SLA-DR|SLA-DRA|SBAB-591C4.7-001 protein taxon:9823 20190601 Ensembl
Public Reference IDs (PMID, PMC, doi, or GO_REF) should be preferred over group specific Reference IDs
UniProtKB F1RGR1 CAMKK1 GO:0005829 Reactome:R-NUL-9619396 TAS C Uncharacterized protein CAMKK1 protein taxon:9823 20180914 Reactome
UniProtKB P24786 NTRK3 GO:0005886 Reactome:R-NUL-9034605 TAS C NT-3 growth factor receptor NTRK3|TRKC protein taxon:9823 20180108 Reactome
UniProtKB P31006 GUK1 GO:0005829 Reactome:R-SSC-2162073 TAS C Guanylate kinase GUK1|GUK protein taxon:9823 20120314 Reactome
UniProtKB P42706 THPO GO:0005576 Reactome:R-NUL-443942 TAS C Thrombopoietin THPO protein taxon:9823 20091019 Reactome
UniProtKB Q00655 SYK GO:0004715 Reactome:R-NUL-437938 TAS F Tyrosine-protein kinase SYK SYK protein taxon:9823 20150728 Reactome
UniProtKB Q00655 SYK GO:0005829 Reactome:R-NUL-437938 TAS C Tyrosine-protein kinase SYK SYK protein taxon:9823 20090918 Reactome
UniProtKB Q00655 SYK GO:0005829 Reactome:R-NUL-437945 TAS C Tyrosine-protein kinase SYK SYK protein taxon:9823 20090918 Reactome
UniProtKB Q29011 ACAN GO:0005576 Reactome:R-NUL-3814821 TAS C Aggrecan core protein ACAN|AGC1 protein taxon:9823 20130828 Reactome
UniProtKB Q29073 PTGR1 GO:0005829 Reactome:R-SSC-2161617 TAS C Prostaglandin reductase 1 PTGR1|LTB4DH protein taxon:9823 20120224 Reactome
UniProtKB Q29073 PTGR1 GO:0005829 Reactome:R-SSC-2161847 TAS C Prostaglandin reductase 1 PTGR1|LTB4DH protein taxon:9823 20120224 Reactome
UniProtKB Q29073 PTGR1 GO:0036185 Reactome:R-SSC-2161847 TAS F Prostaglandin reductase 1 PTGR1|LTB4DH protein taxon:9823 20120417 Reactome
UniProtKB Q29073 PTGR1 GO:0097257 Reactome:R-SSC-2161617 TAS F Prostaglandin reductase 1 PTGR1|LTB4DH protein taxon:9823 20150207 Reactome
UniProtKB Q66T47 ACVR2B GO:1901389 DOI:10.1016/j.procbio.2011.10.027 IMP P Activin receptor type-2B ACVR2B protein taxon:9823 20160111 AgBase