Table of contents
Summary
GAF summary
Found 122395 annotations in 122414 lines.
GAF Validation Summary
Errors are reported first.
For rule GO_AR:0000005 (http://www.geneontology.org/GO.annotation_qc.shtml#GO_AR:0000005)
No ISS or ISS-related annotations to 'protein binding ; GO:0005515', there are 7 violations with type Error.
For rule GO_AR:0000014 (http://www.geneontology.org/GO.annotation_qc.shtml#GO_AR:0000014)
Valid GO term ID, there are 13 violations with type Error.
For rule GO_AR:0000003 (http://www.geneontology.org/GO.annotation_qc.shtml#GO_AR:0000003)
Annotations to 'binding ; GO:0005488' and 'protein binding ; GO:0005515' should be made with IPI and an interactor in the 'with' field, there are 8 violations with type Warning.
GAF Prediction Summary
Found 138 predictions, see prediction file for details.
Used Ontology Summary
go/extensions/go-gaf go/releases/2019-06-08/extensions/go-gaf.owl
Report
Group: goa - Dataset: goa_cow
SUMMARY
This report generated on 2019-06-09
- Associations: 122395
- Lines in file (incl headers): 168106
- Lines skipped: 45699
!gaf-version: 2.1
!
!The set of protein accessions included in this file is based on UniProt reference proteomes, which provide one protein per gene.
!They include the protein sequences annotated in Swiss-Prot or the longest TrEMBL transcript if there is no Swiss-Prot record.
!If a particular protein accession is not annotated with GO, then it will not appear in this file.
!
!Note that the annotation set in this file is filtered in order to reduce redundancy; the full, unfiltered set can be found in
!ftp://ftp.ebi.ac.uk/pub/databases/GO/goa/UNIPROT/goa_uniprot_all.gz
!
!Generated: 2019-06-03 16:53
!GO-version: http://purl.obolibrary.org/obo/go/releases/2019-06-02/extensions/go-plus.owl
!
Contents
gorule-0000008
gorule-0000020
other
MESSAGES
gorule-0000008
No annotations should be made to uninformative high level terms
Messages
- WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms (GO:0005622) --
UniProtKB P81287 ANXA5 GO:0005622 GO_REF:0000024 ISS UniProtKB:P08758 C Annexin A5 ANXA5|ANX5 protein taxon:9913 20061003 AgBase
- WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms (GO:0005622) --
UniProtKB Q2HJ92 PRKRA GO:0005622 GO_REF:0000024 ISS UniProtKB:Q9WTX2 C Interferon-inducible double-stranded RNA-dependent protein kinase activator A PRKRA protein taxon:9913 20070616 AgBase
gorule-0000020
Automatic repair of annotations to merged or obsoleted terms
Messages
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0035068) --
UniProtKB A0A3Q1M249 AGO3 GO:0035068 GO_REF:0000104 IEA UniRule:UR000107558 C Protein argonaute-3 AGO3|EIF2C3 protein taxon:9913 20190601 UniProt
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0035068) --
UniProtKB B0JYP5 AGO2 GO:0035068 GO_REF:0000104 IEA UniRule:UR000107560 C Protein argonaute-2 AGO2|EIF2C2 protein taxon:9913 20190601 UniProt
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0035068) --
UniProtKB F1MCQ5 DICER1 GO:0035068 GO_REF:0000107 IEA UniProtKB:Q9UPY3|ensembl:ENSP00000437256 C Endoribonuclease Dicer DICER1 protein taxon:9913 20190601 Ensembl
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0035068) --
UniProtKB F1MLT5 TNRC6C GO:0035068 PMID:21873635 IBA PANTHER:PTN000989337|UniProtKB:Q8NDV7 C Trinucleotide repeat containing 6C TNRC6C protein taxon:9913 20180720 GO_Central
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0050880) --
UniProtKB F1MVT0 FOXC2 GO:0050880 GO_REF:0000107 IEA UniProtKB:Q61850|ensembl:ENSMUSP00000055290 P Forkhead box C2 FOXC2 protein taxon:9913 20190601 Ensembl
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0035068) --
UniProtKB F1MXK6 AGO4 GO:0035068 GO_REF:0000104 IEA UniRule:UR000106187 C Protein argonaute-4 AGO4|EIF2C4 protein taxon:9913 20190601 UniProt
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0035068) --
UniProtKB F1MXX2 AGO1 GO:0035068 GO_REF:0000107 IEA UniProtKB:Q8CJG1|ensembl:ENSMUSP00000095498 C Argonaute 1, RISC catalytic component AGO1 protein taxon:9913 20190601 Ensembl
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0035068) --
UniProtKB F1MXX2 AGO1 GO:0035068 GO_REF:0000107 IEA UniProtKB:Q9UL18|ensembl:ENSP00000362300 C Argonaute 1, RISC catalytic component AGO1 protein taxon:9913 20190601 Ensembl
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0035068) --
UniProtKB F1MY06 TNRC6B GO:0035068 PMID:21873635 IBA PANTHER:PTN000989337|UniProtKB:Q8NDV7 C Trinucleotide repeat containing 6B TNRC6B protein taxon:9913 20180720 GO_Central
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0035068) --
UniProtKB G3N258 TNRC6A GO:0035068 PMID:21873635 IBA PANTHER:PTN000989337|UniProtKB:Q8NDV7 C Trinucleotide repeat containing 6A TNRC6A protein taxon:9913 20180720 GO_Central
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0050880) --
UniProtKB P01017 AGT GO:0050880 GO_REF:0000037 IEA UniProtKB-KW:KW-0838 P Angiotensinogen AGT|SERPINA8 protein taxon:9913 20190601 UniProt
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0050880) --
UniProtKB P01044 KNG1 GO:0050880 GO_REF:0000037 IEA UniProtKB-KW:KW-0838 P Kininogen-1 KNG1 protein taxon:9913 20190601 UniProt
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0050880) --
UniProtKB P01045 KNG2 GO:0050880 GO_REF:0000037 IEA UniProtKB-KW:KW-0838 P Kininogen-2 KNG2 protein taxon:9913 20190601 UniProt
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0050880) --
UniProtKB P01156 NTS GO:0050880 GO_REF:0000037 IEA UniProtKB-KW:KW-0838 P Neurotensin/neuromedin N NTS protein taxon:9913 20190601 UniProt
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0050880) --
UniProtKB P01180 AVP GO:0050880 GO_REF:0000037 IEA UniProtKB-KW:KW-0838 P Vasopressin-neurophysin 2-copeptin AVP protein taxon:9913 20190601 UniProt
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0050880) --
UniProtKB P07501 NPPA GO:0050880 GO_REF:0000037 IEA UniProtKB-KW:KW-0838 P Natriuretic peptides A NPPA protein taxon:9913 20190601 UniProt
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0050880) --
UniProtKB P13204 NPPB GO:0050880 GO_REF:0000037 IEA UniProtKB-KW:KW-0838 P Natriuretic peptides B NPPB protein taxon:9913 20190601 UniProt
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0050880) --
UniProtKB P17322 EDN1 GO:0050880 GO_REF:0000037 IEA UniProtKB-KW:KW-0838 P Endothelin-1 EDN1 protein taxon:9913 20190601 UniProt
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0050880) --
UniProtKB P55206 NPPC GO:0050880 GO_REF:0000037 IEA UniProtKB-KW:KW-0838 P C-type natriuretic peptide NPPC protein taxon:9913 20190601 UniProt
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:1904265) --
UniProtKB Q05B57 YOD1 GO:1904265 GO_REF:0000002 IEA InterPro:IPR039138 F Ubiquitin thioesterase OTU1 YOD1 protein taxon:9913 20190601 InterPro
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0035068) --
UniProtKB Q0IIG6 TARBP2 GO:0035068 GO_REF:0000024 ISS UniProtKB:Q15633 C RISC-loading complex subunit TARBP2 TARBP2 protein taxon:9913 20170714 UniProt
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0035068) --
UniProtKB Q28141 DHX9 GO:0035068 GO_REF:0000024 ISS UniProtKB:Q08211 C ATP-dependent RNA helicase A DHX9|DDX9|NDH2 protein taxon:9913 20170714 UniProt
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0050880) --
UniProtKB Q2T9Y6 GCLM GO:0050880 GO_REF:0000024 ISS UniProtKB:P48507 P Glutamate--cysteine ligase regulatory subunit GCLM protein taxon:9913 20070105 UniProt
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0050880) --
UniProtKB Q3ZBM4 ITGB1BP1 GO:0050880 GO_REF:0000024 ISS UniProtKB:O14713 P Integrin beta-1-binding protein 1 ITGB1BP1 protein taxon:9913 20130419 UniProt
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0035068) --
UniProtKB Q6QME8 AGO2 GO:0035068 GO_REF:0000024 ISS UniProtKB:Q9UKV8 C Protein argonaute-2 AGO2|EIF2C2 protein taxon:9913 20090421 UniProt
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0035068) --
UniProtKB Q6T5B7 AGO3 GO:0035068 GO_REF:0000104 IEA UniRule:UR000107558 C Protein argonaute-3 AGO3|EIF2C3 protein taxon:9913 20190601 UniProt
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0035068) --
UniProtKB Q6TUI4 DICER1 GO:0035068 GO_REF:0000024 ISS UniProtKB:Q9UPY3 C Endoribonuclease Dicer DICER1|DICER protein taxon:9913 20170714 UniProt
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0050880) --
UniProtKB Q867A9 EDN2 GO:0050880 GO_REF:0000037 IEA UniProtKB-KW:KW-0838 P Endothelin-2 EDN2 protein taxon:9913 20190601 UniProt
other
OWLTools check
#Line number RuleID ViolationType Message Line
#------------
#------------
# Validation for #122395 annotations in 122414 lines
#------------
#Line number RuleID ViolationType Message Line
#------------
# GO_AR:0000005 No ISS or ISS-related annotations to 'protein binding ; GO:0005515' Error count: 7
38513 GO_AR:0000005 Error No ISS or ISS-related annotations to 'protein binding ; GO:0005515' UniProtKB E1BJ75 CRTAP GO:0005515 GO_REF:0000024 ISS UniProtKB:Q90830 F Cartilage associated protein CRTAP protein taxon:9913 20180925 UniProt
81271 GO_AR:0000005 Error No ISS or ISS-related annotations to 'protein binding ; GO:0005515' UniProtKB P08169 IGF2R GO:0005515 GO_REF:0000024 ISS UniProtKB:P11717 F Cation-independent mannose-6-phosphate receptor IGF2R|M6P protein taxon:9913 20091210 UniProt
82890 GO_AR:0000005 Error No ISS or ISS-related annotations to 'protein binding ; GO:0005515' UniProtKB P18341 TGFB1 GO:0005515 GO_REF:0000024 ISS UniProtKB:P01137 F Transforming growth factor beta-1 proprotein TGFB1 protein taxon:9913 20141202 AgBase
88825 GO_AR:0000005 Error No ISS or ISS-related annotations to 'protein binding ; GO:0005515' UniProtKB P80012 VWF GO:0005515 GO_REF:0000024 ISS UniProtKB:P04275 F von Willebrand factor VWF|F8VWF protein taxon:9913 20070328 UniProt
88931 GO_AR:0000005 Error No ISS or ISS-related annotations to 'protein binding ; GO:0005515' UniProtKB P80311 PPIB GO:0005515 GO_REF:0000024 ISS UniProtKB:P24367 F Peptidyl-prolyl cis-trans isomerase B PPIB protein taxon:9913 20180925 UniProt
108449 GO_AR:0000005 Error No ISS or ISS-related annotations to 'protein binding ; GO:0005515' UniProtKB Q3MHX6 OS9 GO:0005515 GO_REF:0000024 ISS UniProtKB:Q13438 F Protein OS-9 OS9 protein taxon:9913 20090907 UniProt
108905 GO_AR:0000005 Error No ISS or ISS-related annotations to 'protein binding ; GO:0005515' UniProtKB Q3SX24 FBXO6 GO:0005515 GO_REF:0000024 ISS UniProtKB:Q9QZN4 F F-box only protein 6 FBXO6|FBS2|FBX6 protein taxon:9913 20090903 UniProt
#------------
# GO_AR:0000014 Valid GO term ID Error count: 13
79692 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0010867 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001013),has_agent(UBERON:0002107),occurs_in(UBERON:0001911)
79692 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0010867 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001013),has_agent(UBERON:0002107),occurs_in(UBERON:0001911)
79702 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0045542 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001013),has_agent(UBERON:0002107),occurs_in(UBERON:0001911)
79702 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0045542 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001013),has_agent(UBERON:0002107),occurs_in(UBERON:0001911)
79704 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0045723 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001911),has_agent(UBERON:0002107),occurs_in(UBERON:0001013)
79704 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0045723 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001911),has_agent(UBERON:0002107),occurs_in(UBERON:0001013)
79705 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0045723 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001013),has_agent(UBERON:0002107),occurs_in(UBERON:0001911)
79705 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0045723 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001013),has_agent(UBERON:0002107),occurs_in(UBERON:0001911)
79710 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0071073 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001911),has_agent(UBERON:0002107),occurs_in(UBERON:0001013)
79710 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0071073 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001911),has_agent(UBERON:0002107),occurs_in(UBERON:0001013)
79711 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:1900482 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001013),has_agent(UBERON:0002107),occurs_in(UBERON:0001911)
79711 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:1900482 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001013),has_agent(UBERON:0002107),occurs_in(UBERON:0001911)
97213 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB Q17R14 MYO1D GO:0061502 GO_REF:0000024 ISS UniProtKB:F1PRN2 P Unconventional myosin-Id MYO1D protein taxon:9913 20140311 UniProt has_agent(GO:0005884)
#------------
# GO_AR:0000003 Annotations to 'binding ; GO:0005488' and 'protein binding ; GO:0005515' should be made with IPI and an interactor in the 'with' field Warning count: 8
38513 GO_AR:0000003 Warning Annotations to 'binding' (GO:0005488) and 'protein binding' (GO:0005515) should be made with an IPI evidence code and the interactor in the 'with' field UniProtKB E1BJ75 CRTAP GO:0005515 GO_REF:0000024 ISS UniProtKB:Q90830 F Cartilage associated protein CRTAP protein taxon:9913 20180925 UniProt
80464 GO_AR:0000003 Warning Annotations to 'binding' (GO:0005488) and 'protein binding' (GO:0005515) should be made with an IPI evidence code and the interactor in the 'with' field UniProtKB P04272 ANXA2 GO:0005515 PMID:18597635 TAS F Annexin A2 ANXA2|ANX2 protein taxon:9913 20140514 AgBase
81271 GO_AR:0000003 Warning Annotations to 'binding' (GO:0005488) and 'protein binding' (GO:0005515) should be made with an IPI evidence code and the interactor in the 'with' field UniProtKB P08169 IGF2R GO:0005515 GO_REF:0000024 ISS UniProtKB:P11717 F Cation-independent mannose-6-phosphate receptor IGF2R|M6P protein taxon:9913 20091210 UniProt
82890 GO_AR:0000003 Warning Annotations to 'binding' (GO:0005488) and 'protein binding' (GO:0005515) should be made with an IPI evidence code and the interactor in the 'with' field UniProtKB P18341 TGFB1 GO:0005515 GO_REF:0000024 ISS UniProtKB:P01137 F Transforming growth factor beta-1 proprotein TGFB1 protein taxon:9913 20141202 AgBase
88825 GO_AR:0000003 Warning Annotations to 'binding' (GO:0005488) and 'protein binding' (GO:0005515) should be made with an IPI evidence code and the interactor in the 'with' field UniProtKB P80012 VWF GO:0005515 GO_REF:0000024 ISS UniProtKB:P04275 F von Willebrand factor VWF|F8VWF protein taxon:9913 20070328 UniProt
88931 GO_AR:0000003 Warning Annotations to 'binding' (GO:0005488) and 'protein binding' (GO:0005515) should be made with an IPI evidence code and the interactor in the 'with' field UniProtKB P80311 PPIB GO:0005515 GO_REF:0000024 ISS UniProtKB:P24367 F Peptidyl-prolyl cis-trans isomerase B PPIB protein taxon:9913 20180925 UniProt
108449 GO_AR:0000003 Warning Annotations to 'binding' (GO:0005488) and 'protein binding' (GO:0005515) should be made with an IPI evidence code and the interactor in the 'with' field UniProtKB Q3MHX6 OS9 GO:0005515 GO_REF:0000024 ISS UniProtKB:Q13438 F Protein OS-9 OS9 protein taxon:9913 20090907 UniProt
108905 GO_AR:0000003 Warning Annotations to 'binding' (GO:0005488) and 'protein binding' (GO:0005515) should be made with an IPI evidence code and the interactor in the 'with' field UniProtKB Q3SX24 FBXO6 GO:0005515 GO_REF:0000024 ISS UniProtKB:Q9QZN4 F F-box only protein 6 FBXO6|FBS2|FBX6 protein taxon:9913 20090903 UniProt
#------------
Predictions
GO:0005623 cell AnnotationPropagation C GO:1990126 retrograde transport, endosome to plasma membrane ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway ISS
GO:0043985 histone H4-R3 methylation AnnotationPropagation P GO:0044020 histone methyltransferase activity (H4-R3 specific) ISS
GO:0035246 peptidyl-arginine N-methylation AnnotationPropagation P GO:0044020 histone methyltransferase activity (H4-R3 specific) ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0070124 mitochondrial translational initiation IDA
GO:0005623 cell AnnotationPropagation C GO:1990126 retrograde transport, endosome to plasma membrane ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway ISS
GO:0005623 cell AnnotationPropagation C GO:0035356 cellular triglyceride homeostasis ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0005623 cell AnnotationPropagation C GO:0051452 intracellular pH reduction ISS
GO:0006479 protein methylation AnnotationPropagation P GO:0071885 N-terminal protein N-methyltransferase activity ISS
GO:0016310 phosphorylation AnnotationPropagation P GO:0051736 ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity ISS
GO:0010950 positive regulation of endopeptidase activity AnnotationPropagation P GO:0061133 endopeptidase activator activity ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0006508 proteolysis AnnotationPropagation P GO:0036459 thiol-dependent ubiquitinyl hydrolase activity ISS
GO:0006508 proteolysis AnnotationPropagation P GO:0070573 metallodipeptidase activity ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0005739 mitochondrion AnnotationPropagation C GO:0070126 mitochondrial translational termination ISS
GO:0005623 cell AnnotationPropagation C GO:1990036 calcium ion import into sarcoplasmic reticulum ISS
GO:0005737 cytoplasm AnnotationPropagation C GO:1990036 calcium ion import into sarcoplasmic reticulum ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0005623 cell AnnotationPropagation C GO:0090110 COPII-coated vesicle cargo loading ISS
GO:0016020 membrane AnnotationPropagation C GO:0090110 COPII-coated vesicle cargo loading ISS
GO:0005623 cell AnnotationPropagation C GO:0071333 cellular response to glucose stimulus ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0032259 methylation AnnotationPropagation P GO:0046539 histamine N-methyltransferase activity ISS
GO:0005623 cell AnnotationPropagation C GO:0090110 COPII-coated vesicle cargo loading ISS
GO:0016020 membrane AnnotationPropagation C GO:0090110 COPII-coated vesicle cargo loading ISS
GO:0007186 G protein-coupled receptor signaling pathway AnnotationPropagation P GO:0070915 lysophosphatidic acid receptor activity ISS
GO:0005623 cell AnnotationPropagation C GO:1990126 retrograde transport, endosome to plasma membrane ISS
GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic AnnotationPropagation P GO:0090624 endoribonuclease activity, cleaving miRNA-paired mRNA ISS
GO:0035279 mRNA cleavage involved in gene silencing by miRNA AnnotationPropagation P GO:0090624 endoribonuclease activity, cleaving miRNA-paired mRNA ISS
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0102758 very-long-chain enoyl-CoA reductase activity ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:1990180 mitochondrial tRNA 3'-end processing ISS
GO:0005764 lysosome AnnotationPropagation C GO:1905146 lysosomal protein catabolic process ISS
GO:0006508 proteolysis AnnotationPropagation P GO:0070006 metalloaminopeptidase activity ISS
GO:0030974 thiamine pyrophosphate transmembrane transport AnnotationPropagation P GO:0090422 thiamine pyrophosphate transmembrane transporter activity ISS
GO:0035461 vitamin transmembrane transport AnnotationPropagation P GO:0090422 thiamine pyrophosphate transmembrane transporter activity ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0005623 cell AnnotationPropagation C GO:0051310 metaphase plate congression ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0005623 cell AnnotationPropagation C GO:0051480 regulation of cytosolic calcium ion concentration ISS
GO:0005623 cell AnnotationPropagation C GO:0061015 snRNA import into nucleus ISS
GO:0005623 cell AnnotationPropagation C GO:0042073 intraciliary transport ISS
GO:0005929 cilium AnnotationPropagation C GO:0042073 intraciliary transport ISS
GO:0016567 protein ubiquitination AnnotationPropagation P GO:0061630 ubiquitin protein ligase activity ISS
GO:0005623 cell AnnotationPropagation C GO:0045046 protein import into peroxisome membrane ISS
GO:0005623 cell AnnotationPropagation C GO:0051168 nuclear export ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0033617 mitochondrial respiratory chain complex IV assembly ISS
GO:0007165 signal transduction AnnotationPropagation P GO:0005179 hormone activity IMP
GO:0005623 cell AnnotationPropagation C GO:0051281 positive regulation of release of sequestered calcium ion into cytosol ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0070901 mitochondrial tRNA methylation ISS
GO:0007268 chemical synaptic transmission AnnotationPropagation P GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential IMP
GO:0034220 ion transmembrane transport AnnotationPropagation P GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential IMP
GO:0060078 regulation of postsynaptic membrane potential AnnotationPropagation P GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential IMP
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0016311 dephosphorylation AnnotationPropagation P GO:0052834 inositol monophosphate phosphatase activity IDA
GO:0005739 mitochondrion AnnotationPropagation C GO:0097345 mitochondrial outer membrane permeabilization ISS
GO:0051726 regulation of cell cycle AnnotationPropagation P GO:0097472 cyclin-dependent protein kinase activity ISS
GO:0006468 protein phosphorylation AnnotationPropagation P GO:0097472 cyclin-dependent protein kinase activity ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0016310 phosphorylation AnnotationPropagation P GO:0008887 glycerate kinase activity ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0070145 mitochondrial asparaginyl-tRNA aminoacylation ISS
GO:0035513 oxidative RNA demethylation AnnotationPropagation P GO:1990930 RNA N1-methyladenosine dioxygenase activity ISS
GO:0016311 dephosphorylation AnnotationPropagation P GO:0043874 acireductone synthase activity ISS
GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine AnnotationPropagation P GO:0035243 protein-arginine omega-N symmetric methyltransferase activity ISS
GO:0006412 translation AnnotationPropagation P GO:0008135 translation factor activity, RNA binding ISS
GO:0006417 regulation of translation AnnotationPropagation P GO:0008135 translation factor activity, RNA binding ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0006412 translation AnnotationPropagation P GO:0008079 translation termination factor activity ISS
GO:0006415 translational termination AnnotationPropagation P GO:0008079 translation termination factor activity ISS
GO:0006417 regulation of translation AnnotationPropagation P GO:0008079 translation termination factor activity ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0033617 mitochondrial respiratory chain complex IV assembly ISS
GO:0035513 oxidative RNA demethylation AnnotationPropagation P GO:1990931 RNA N6-methyladenosine dioxygenase activity ISS
GO:0098734 macromolecule depalmitoylation AnnotationPropagation P GO:0008474 palmitoyl-(protein) hydrolase activity ISS
GO:0016311 dephosphorylation AnnotationPropagation P GO:0098519 nucleotide phosphatase activity, acting on free nucleotides ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0033617 mitochondrial respiratory chain complex IV assembly ISS
GO:0006508 proteolysis AnnotationPropagation P GO:0070006 metalloaminopeptidase activity ISS
GO:0005623 cell AnnotationPropagation C GO:1903445 protein transport from ciliary membrane to plasma membrane ISS
GO:0016020 membrane AnnotationPropagation C GO:1903445 protein transport from ciliary membrane to plasma membrane ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0097345 mitochondrial outer membrane permeabilization ISS
GO:0006470 protein dephosphorylation AnnotationPropagation P GO:0101006 protein histidine phosphatase activity IDA
GO:0043085 positive regulation of catalytic activity AnnotationPropagation P GO:0060230 lipoprotein lipase activator activity NAS
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0005623 cell AnnotationPropagation C GO:0006878 cellular copper ion homeostasis ISS
GO:0070933 histone H4 deacetylation AnnotationPropagation P GO:0097372 NAD-dependent histone deacetylase activity (H3-K18 specific) ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0090615 mitochondrial mRNA processing ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0033617 mitochondrial respiratory chain complex IV assembly ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0070330 aromatase activity ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0097345 mitochondrial outer membrane permeabilization ISS
GO:0010452 histone H3-K36 methylation AnnotationPropagation P GO:0046975 histone methyltransferase activity (H3-K36 specific) ISS
GO:0016310 phosphorylation AnnotationPropagation P GO:0051731 polynucleotide 5'-hydroxyl-kinase activity ISS
GO:0006897 endocytosis AnnotationPropagation P GO:0070287 ferritin receptor activity ISS
GO:0016567 protein ubiquitination AnnotationPropagation P GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death ISS
GO:0005623 cell AnnotationPropagation C GO:1990126 retrograde transport, endosome to plasma membrane ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0005739 mitochondrion AnnotationPropagation C GO:0042407 cristae formation ISS
GO:0016311 dephosphorylation AnnotationPropagation P GO:0098519 nucleotide phosphatase activity, acting on free nucleotides ISS
GO:0005623 cell AnnotationPropagation C GO:0090110 COPII-coated vesicle cargo loading ISS
GO:0016020 membrane AnnotationPropagation C GO:0090110 COPII-coated vesicle cargo loading ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0034553 mitochondrial respiratory chain complex II assembly ISS
GO:0006468 protein phosphorylation AnnotationPropagation P GO:0050254 rhodopsin kinase activity ISS
GO:0005623 cell AnnotationPropagation C GO:1990126 retrograde transport, endosome to plasma membrane ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0005739 mitochondrion AnnotationPropagation C GO:0070124 mitochondrial translational initiation ISS
GO:0005623 cell AnnotationPropagation C GO:0051560 mitochondrial calcium ion homeostasis ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0051560 mitochondrial calcium ion homeostasis ISS
GO:0006468 protein phosphorylation AnnotationPropagation P GO:0098821 BMP receptor activity ISS
GO:0030509 BMP signaling pathway AnnotationPropagation P GO:0098821 BMP receptor activity ISS
GO:0005623 cell AnnotationPropagation C GO:0060402 calcium ion transport into cytosol ISS
GO:0036065 fucosylation AnnotationPropagation P GO:0046920 alpha-(1->3)-fucosyltransferase activity ISS
GO:0005623 cell AnnotationPropagation C GO:1903445 protein transport from ciliary membrane to plasma membrane ISS
GO:0016020 membrane AnnotationPropagation C GO:1903445 protein transport from ciliary membrane to plasma membrane ISS
GO:0005623 cell AnnotationPropagation C GO:0006626 protein targeting to mitochondrion ISS
GO:0035435 phosphate ion transmembrane transport AnnotationPropagation P GO:0061513 glucose 6-phosphate:inorganic phosphate antiporter activity ISS
GO:0015712 hexose phosphate transport AnnotationPropagation P GO:0061513 glucose 6-phosphate:inorganic phosphate antiporter activity ISS
GO:0015711 organic anion transport AnnotationPropagation P GO:0061513 glucose 6-phosphate:inorganic phosphate antiporter activity ISS
GO:0005623 cell AnnotationPropagation C GO:0051168 nuclear export ISS
GO:0007268 chemical synaptic transmission AnnotationPropagation P GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential IMP
GO:0034220 ion transmembrane transport AnnotationPropagation P GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential IMP
GO:0060078 regulation of postsynaptic membrane potential AnnotationPropagation P GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential IMP
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0031594 neuromuscular junction FoldBasedPredictor GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential occurs_in GO:0031594 neuromuscular junction occurs_in UBERON:0000061 anatomical structure IMP
GO:0033267 axon part FoldBasedPredictor GO:0098793 presynapse part_of GO:0030424 axon part_of UBERON:0002037 cerebellum IDA
GO:0071499 cellular response to laminar fluid shear stress FoldBasedPredictor GO:1903038 negative regulation of leukocyte cell-cell adhesion occurs_in CL:0002544 part_of GO:0071499 cellular response to laminar fluid shear stress IMP
GO:0098684 photoreceptor ribbon synapse FoldBasedPredictor GO:0098831 presynaptic active zone cytoplasmic component part_of GO:0098684 photoreceptor ribbon synapse part_of UBERON:0000061 anatomical structure IDA
GO:0031594 neuromuscular junction FoldBasedPredictor GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential occurs_in GO:0031594 neuromuscular junction occurs_in UBERON:0000061 anatomical structure IMP
GO:0042583 chromaffin granule FoldBasedPredictor GO:0097159 organic cyclic compound binding occurs_in GO:0042583 chromaffin granule IDA
Predictions (experimental)