• Summary (original)
• Report (original)
• OWLTools check (original)
• Predictions (original)
• Predictions (experimental) (original)

GAF summary

Found 13460 annotations in 13479 lines.

GAF Validation Summary Errors are reported first.

For rule GO_AR:0000005 (http://www.geneontology.org/GO.annotation_qc.shtml#GO_AR:0000005) No ISS or ISS-related annotations to 'protein binding ; GO:0005515', there is one violation with type Error.

For rule GO_AR:0000003 (http://www.geneontology.org/GO.annotation_qc.shtml#GO_AR:0000003) Annotations to 'binding ; GO:0005488' and 'protein binding ; GO:0005515' should be made with IPI and an interactor in the 'with' field, there is one violation with type Warning.

GAF Prediction Summary

Found 6 predictions, see prediction file for details.

Used Ontology Summary

go/extensions/go-gaf

Group: goa - Dataset: goa_cow_isoform

SUMMARY

This report generated on 2019-04-17

• Associations: 13460
• Lines in file (incl headers): 21643
• Lines skipped: 8171

Header From Original Association File

!gaf-version: 2.1
!
!The set of protein accessions included in this file is based on UniProt complete proteomes, which may provide more than one protein per gene.
!They include all Swiss-Prot entries for the species plus any TrEMBL entries that have an Ensembl DR line. The TrEMBL entries are likely to overlap with the Swiss-Prot entries or their isoforms.
!If a particular protein accession is not annotated with GO, then it will not appear in this file.
!
!Note that the annotation set in this file is filtered in order to reduce redundancy; the full, unfiltered set can be found in
!ftp://ftp.ebi.ac.uk/pub/databases/GO/goa/UNIPROT/goa_uniprot_all.gaf.gz
!
!Generated: 2019-04-08 12:02
!GO-version: http://purl.obolibrary.org/obo/go/releases/2019-03-29/extensions/go-plus.owl
!

Contents

gorule-0000008

gorule-0000020

other

MESSAGES

gorule-0000008

No annotations should be made to uninformative high level terms

• total: 2

Messages

• WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms (GO:0005215) -- UniProtKB A0A3Q1MUJ2 SLC22A12 GO:0005215 GO_REF:0000002 IEA InterPro:IPR005829 F Solute carrier family 22 member 12 SLC22A12 protein taxon:9913 20190406 InterPro UniProtKB:E1BAB1
• WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms (GO:0005215) -- UniProtKB E1B8V0 SLC13A5 GO:0005215 GO_REF:0000002 IEA InterPro:IPR001898 F Uncharacterized protein SLC13A5 protein taxon:9913 20190406 InterPro UniProtKB:G3MY69

gorule-0000020

Automatic repair of annotations to merged or obsoleted terms

• total: 8

Messages

• WARNING - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0008565) -- UniProtKB A0A3Q1LV36 IPO5 GO:0008565 PMID:21873635 IBA MGI:MGI:107532|MGI:MGI:1917822|PANTHER:PTN000055427|SGD:S000000912|SGD:S000004339|SGD:S000004925|TAIR:locus:2039410|TAIR:locus:2168586 F Uncharacterized protein IPO5 protein taxon:9913 20170228 GO_Central UniProtKB:F1MPE5
• WARNING - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0008565) -- UniProtKB A0A3Q1MSA5 VPS26B GO:0008565 PMID:21873635 IBA PANTHER:PTN000260563|SGD:S000003589 F Uncharacterized protein VPS26B protein taxon:9913 20170228 GO_Central UniProtKB:E1BMM4
• WARNING - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0008565) -- UniProtKB A0A3Q1MUS6 KPNA3 GO:0008565 GO_REF:0000002 IEA InterPro:IPR036975 F Importin subunit alpha KPNA3 protein taxon:9913 20190406 InterPro UniProtKB:F1MIZ9
• WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0015238) -- UniProtKB A0A3Q1MWZ9 SLC47A2 GO:0015238 PMID:21873635 IBA PANTHER:PTN000129048|RGD:1311123|TAIR:locus:2050190 F Multidrug and toxin extrusion protein SLC47A2 protein taxon:9913 20170228 GO_Central UniProtKB:E1BIJ2
• WARNING - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0008565) -- UniProtKB A0A3Q1N3C7 IPO4 GO:0008565 PMID:21873635 IBA MGI:MGI:107532|MGI:MGI:1917822|PANTHER:PTN000055427|SGD:S000000912|SGD:S000004339|SGD:S000004925|TAIR:locus:2039410|TAIR:locus:2168586 F IPO4 protein IPO4 protein taxon:9913 20170228 GO_Central UniProtKB:A4IFB8
• WARNING - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0008565) -- UniProtKB Q3SYU7 TNPO1 GO:0008565 PMID:21873635 IBA MGI:MGI:107532|MGI:MGI:1917822|PANTHER:PTN000055427|SGD:S000000912|SGD:S000004339|SGD:S000004925|TAIR:locus:2039410|TAIR:locus:2168586 F Transportin-1 TNPO1 protein taxon:9913 20170228 GO_Central UniProtKB:F1MMY6
• WARNING - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0008565) -- UniProtKB Q3T0M0 VPS29 contributes_to GO:0008565 PMID:21873635 IBA PANTHER:PTN000122547|SGD:S000001054 F Vacuolar protein sorting-associated protein 29 VPS29 protein taxon:9913 20170228 GO_Central UniProtKB:G3X6P5
• WARNING - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0008565) -- UniProtKB Q3ZBN8 DNAJC19 contributes_to GO:0008565 PMID:21873635 IBA PANTHER:PTN000298641|SGD:S000005272 F Mitochondrial import inner membrane translocase subunit TIM14 DNAJC19 protein taxon:9913 20170228 GO_Central UniProtKB:F1MVW6

other

• total: 0

#Line number RuleID ViolationType Message Line
#------------
#------------
# Validation for #13460 annotations in 13479 lines
#------------
#Line number RuleID ViolationType Message Line
#------------
# GO_AR:0000005 No ISS or ISS-related annotations to 'protein binding ; GO:0005515' Error count: 1
5322 GO_AR:0000005 Error No ISS or ISS-related annotations to 'protein binding ; GO:0005515' UniProtKB A0A3Q1N449 TGFB1 GO:0005515 GO_REF:0000024 ISS UniProtKB:P01137 F Transforming growth factor beta TGFB1 protein taxon:9913 20141202 AgBase UniProtKB:E1BNK3
#------------
# GO_AR:0000003 Annotations to 'binding ; GO:0005488' and 'protein binding ; GO:0005515' should be made with IPI and an interactor in the 'with' field Warning count: 1
5322 GO_AR:0000003 Warning Annotations to 'binding' (GO:0005488) and 'protein binding' (GO:0005515) should be made with an IPI evidence code and the interactor in the 'with' field UniProtKB A0A3Q1N449 TGFB1 GO:0005515 GO_REF:0000024 ISS UniProtKB:P01137 F Transforming growth factor beta TGFB1 protein taxon:9913 20141202 AgBase UniProtKB:E1BNK3
#------------

GO:0005623 cell AnnotationPropagation C GO:0097277 cellular urea homeostasis ISS
GO:0009967 positive regulation of signal transduction AnnotationPropagation P GO:0030160 GKAP/Homer scaffold activity ISS
GO:0005623 cell AnnotationPropagation C GO:0030970 retrograde protein transport, ER to cytosol ISS
GO:0005737 cytoplasm AnnotationPropagation C GO:0030970 retrograde protein transport, ER to cytosol ISS
GO:0005623 cell AnnotationPropagation C GO:0032596 protein transport into membrane raft IMP
GO:0016020 membrane AnnotationPropagation C GO:0032596 protein transport into membrane raft IMP