GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0008395 steroid hydroxylase activity IBA GO:0061025 membrane fusion AnnotationPropagation P GO:0005484 SNAP receptor activity IBA GO:0000413 protein peptidyl-prolyl isomerization AnnotationPropagation P GO:0003755 peptidyl-prolyl cis-trans isomerase activity IBA GO:0007165 signal transduction AnnotationPropagation P GO:0004888 transmembrane signaling receptor activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0035556 intracellular signal transduction IBA GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA GO:0043085 positive regulation of catalytic activity AnnotationPropagation P GO:0008047 enzyme activator activity IBA GO:0098793 presynapse AnnotationPropagation C GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane IBA GO:0043547 positive regulation of GTPase activity AnnotationPropagation P GO:0005096 GTPase activator activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0000055 ribosomal large subunit export from nucleus IBA GO:0005623 cell AnnotationPropagation C GO:0000055 ribosomal large subunit export from nucleus IBA GO:0043086 negative regulation of catalytic activity AnnotationPropagation P GO:0055105 ubiquitin-protein transferase inhibitor activity IBA GO:0031397 negative regulation of protein ubiquitination AnnotationPropagation P GO:0055105 ubiquitin-protein transferase inhibitor activity IBA GO:0000165 MAPK cascade AnnotationPropagation P GO:0008349 MAP kinase kinase kinase kinase activity IBA GO:0000185 activation of MAPKKK activity AnnotationPropagation P GO:0008349 MAP kinase kinase kinase kinase activity IBA GO:0006508 proteolysis AnnotationPropagation P GO:0004252 serine-type endopeptidase activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0035329 hippo signaling IBA GO:0015732 prostaglandin transport AnnotationPropagation P GO:0015132 prostaglandin transmembrane transporter activity IBA GO:1905039 carboxylic acid transmembrane transport AnnotationPropagation P GO:0015132 prostaglandin transmembrane transporter activity IBA GO:0010951 negative regulation of endopeptidase activity AnnotationPropagation P GO:0004867 serine-type endopeptidase inhibitor activity IBA GO:0032775 DNA methylation on adenine AnnotationPropagation P GO:0009007 site-specific DNA-methyltransferase (adenine-specific) activity IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0016618 hydroxypyruvate reductase activity IBA GO:0043666 regulation of phosphoprotein phosphatase activity AnnotationPropagation P GO:0019888 protein phosphatase regulator activity IBA GO:0055085 transmembrane transport AnnotationPropagation P GO:0055077 gap junction hemi-channel activity IMP GO:0006412 translation AnnotationPropagation P GO:0030533 triplet codon-amino acid adaptor activity ISS GO:0098655 cation transmembrane transport AnnotationPropagation P GO:0022850 serotonin-gated cation-selective channel activity IBA GO:0007165 signal transduction AnnotationPropagation P GO:0022850 serotonin-gated cation-selective channel activity IBA GO:0006470 protein dephosphorylation AnnotationPropagation P GO:0008420 CTD phosphatase activity IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0003995 acyl-CoA dehydrogenase activity IBA GO:0016311 dephosphorylation AnnotationPropagation P GO:0042577 lipid phosphatase activity IBA GO:0016311 dephosphorylation AnnotationPropagation P GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity IBA GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process AnnotationPropagation P GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity IBA GO:0018108 peptidyl-tyrosine phosphorylation AnnotationPropagation P GO:0004715 non-membrane spanning protein tyrosine kinase activity IBA GO:0007165 signal transduction AnnotationPropagation P GO:0004888 transmembrane signaling receptor activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0010970 transport along microtubule IBA GO:0005623 cell AnnotationPropagation C GO:0010970 transport along microtubule IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen IDA GO:0000413 protein peptidyl-prolyl isomerization AnnotationPropagation P GO:0003755 peptidyl-prolyl cis-trans isomerase activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0038066 p38MAPK cascade ISS GO:0006355 regulation of transcription, DNA-templated AnnotationPropagation P GO:0003700 DNA binding transcription factor activity IBA GO:0070588 calcium ion transmembrane transport AnnotationPropagation P GO:0005262 calcium channel activity IBA GO:0071557 histone H3-K27 demethylation AnnotationPropagation P GO:0071558 histone demethylase activity (H3-K27 specific) ISS GO:0019221 cytokine-mediated signaling pathway AnnotationPropagation P GO:0030368 interleukin-17 receptor activity IBA GO:0006412 translation AnnotationPropagation P GO:0030533 triplet codon-amino acid adaptor activity ISS GO:0016567 protein ubiquitination AnnotationPropagation P GO:0061630 ubiquitin protein ligase activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0006913 nucleocytoplasmic transport IBA GO:0005623 cell AnnotationPropagation C GO:0006913 nucleocytoplasmic transport IBA GO:0005622 intracellular AnnotationPropagation C GO:0007097 nuclear migration IBA GO:0005623 cell AnnotationPropagation C GO:0007097 nuclear migration IBA GO:0015914 phospholipid transport AnnotationPropagation P GO:1990050 phosphatidic acid transporter activity IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0008395 steroid hydroxylase activity IBA GO:0035435 phosphate ion transmembrane transport AnnotationPropagation P GO:0015114 phosphate ion transmembrane transporter activity ISS GO:0006508 proteolysis AnnotationPropagation P GO:0004252 serine-type endopeptidase activity IBA GO:0000165 MAPK cascade AnnotationPropagation P GO:0008349 MAP kinase kinase kinase kinase activity IBA GO:0000185 activation of MAPKKK activity AnnotationPropagation P GO:0008349 MAP kinase kinase kinase kinase activity IBA GO:0030424 axon AnnotationPropagation C GO:0098958 retrograde axonal transport of mitochondrion IMP GO:0005622 intracellular AnnotationPropagation C GO:0098958 retrograde axonal transport of mitochondrion IMP GO:0005623 cell AnnotationPropagation C GO:0098958 retrograde axonal transport of mitochondrion IMP GO:1904115 axon cytoplasm AnnotationPropagation C GO:0098958 retrograde axonal transport of mitochondrion IMP GO:0009967 positive regulation of signal transduction AnnotationPropagation P GO:0005070 SH3/SH2 adaptor activity IBA GO:0007186 G-protein coupled receptor signaling pathway AnnotationPropagation P GO:0008020 G-protein coupled photoreceptor activity IBA GO:0009584 detection of visible light AnnotationPropagation P GO:0008020 G-protein coupled photoreceptor activity IBA GO:0010469 regulation of signaling receptor activity AnnotationPropagation P GO:0005125 cytokine activity IBA GO:0034414 tRNA 3'-trailer cleavage, endonucleolytic AnnotationPropagation P GO:0042781 3'-tRNA processing endoribonuclease activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0031098 stress-activated protein kinase signaling cascade IBA GO:0010951 negative regulation of endopeptidase activity AnnotationPropagation P GO:0004866 endopeptidase inhibitor activity IBA GO:0043547 positive regulation of GTPase activity AnnotationPropagation P GO:0005096 GTPase activator activity IBA GO:0007165 signal transduction AnnotationPropagation P GO:0004888 transmembrane signaling receptor activity IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0016491 oxidoreductase activity IBA GO:0018108 peptidyl-tyrosine phosphorylation AnnotationPropagation P GO:0004715 non-membrane spanning protein tyrosine kinase activity IBA GO:0006278 RNA-dependent DNA biosynthetic process AnnotationPropagation P GO:0003964 RNA-directed DNA polymerase activity IBA GO:0007186 G-protein coupled receptor signaling pathway AnnotationPropagation P GO:0001594 trace-amine receptor activity IDA GO:0005622 intracellular AnnotationPropagation C GO:0031098 stress-activated protein kinase signaling cascade IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0030267 glyoxylate reductase (NADP) activity IBA GO:0006355 regulation of transcription, DNA-templated AnnotationPropagation P GO:0003700 DNA binding transcription factor activity IBA GO:0015031 protein transport AnnotationPropagation P GO:0008565 protein transporter activity IBA GO:0005623 cell AnnotationPropagation C GO:0051453 regulation of intracellular pH IGI GO:0010951 negative regulation of endopeptidase activity AnnotationPropagation P GO:0004867 serine-type endopeptidase inhibitor activity IBA GO:0098655 cation transmembrane transport AnnotationPropagation P GO:0022850 serotonin-gated cation-selective channel activity IBA GO:0007165 signal transduction AnnotationPropagation P GO:0022850 serotonin-gated cation-selective channel activity IBA GO:0007165 signal transduction AnnotationPropagation P GO:0004888 transmembrane signaling receptor activity IBA GO:0015711 organic anion transport AnnotationPropagation P GO:0015347 sodium-independent organic anion transmembrane transporter activity IBA GO:0098656 anion transmembrane transport AnnotationPropagation P GO:0015347 sodium-independent organic anion transmembrane transporter activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0006886 intracellular protein transport IBA GO:0005623 cell AnnotationPropagation C GO:0006886 intracellular protein transport IBA GO:0006412 translation AnnotationPropagation P GO:0030533 triplet codon-amino acid adaptor activity ISS GO:0005622 intracellular AnnotationPropagation C GO:0031098 stress-activated protein kinase signaling cascade IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0008395 steroid hydroxylase activity IBA GO:0010951 negative regulation of endopeptidase activity AnnotationPropagation P GO:0004867 serine-type endopeptidase inhibitor activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0038203 TORC2 signaling IBA GO:0007165 signal transduction AnnotationPropagation P GO:0004888 transmembrane signaling receptor activity IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0016491 oxidoreductase activity IBA GO:0034969 histone arginine methylation AnnotationPropagation P GO:0008469 histone-arginine N-methyltransferase activity IBA GO:0035246 peptidyl-arginine N-methylation AnnotationPropagation P GO:0008469 histone-arginine N-methyltransferase activity IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0008395 steroid hydroxylase activity IBA GO:0005623 cell AnnotationPropagation C GO:0048488 synaptic vesicle endocytosis IBA GO:0045202 synapse AnnotationPropagation C GO:0048488 synaptic vesicle endocytosis IBA GO:0090481 pyrimidine nucleotide-sugar transmembrane transport AnnotationPropagation P GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity IBA GO:0015914 phospholipid transport AnnotationPropagation P GO:0017128 phospholipid scramblase activity IBA GO:0017121 phospholipid scrambling AnnotationPropagation P GO:0017128 phospholipid scramblase activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0006886 intracellular protein transport IBA GO:0005623 cell AnnotationPropagation C GO:0006886 intracellular protein transport IBA GO:0007186 G-protein coupled receptor signaling pathway AnnotationPropagation P GO:0001594 trace-amine receptor activity IBA GO:0007186 G-protein coupled receptor signaling pathway AnnotationPropagation P GO:0008020 G-protein coupled photoreceptor activity IBA GO:0009584 detection of visible light AnnotationPropagation P GO:0008020 G-protein coupled photoreceptor activity IBA GO:0043547 positive regulation of GTPase activity AnnotationPropagation P GO:0005096 GTPase activator activity IBA GO:0051974 negative regulation of telomerase activity AnnotationPropagation P GO:0010521 telomerase inhibitor activity IBA GO:0006508 proteolysis AnnotationPropagation P GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process IBA GO:0006915 apoptotic process AnnotationPropagation P GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process IBA GO:0016567 protein ubiquitination AnnotationPropagation P GO:0004842 ubiquitin-protein transferase activity IBA GO:0043547 positive regulation of GTPase activity AnnotationPropagation P GO:0005096 GTPase activator activity IBA GO:0019221 cytokine-mediated signaling pathway AnnotationPropagation P GO:0030368 interleukin-17 receptor activity IBA GO:0010951 negative regulation of endopeptidase activity AnnotationPropagation P GO:0004867 serine-type endopeptidase inhibitor activity IBA GO:0006366 transcription by RNA polymerase II AnnotationPropagation P GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA GO:0045944 positive regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA GO:0006366 transcription by RNA polymerase II AnnotationPropagation P GO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IBA GO:0045944 positive regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IBA GO:0016567 protein ubiquitination AnnotationPropagation P GO:0061630 ubiquitin protein ligase activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0006406 mRNA export from nucleus IBA GO:0005623 cell AnnotationPropagation C GO:0006406 mRNA export from nucleus IBA GO:0007186 G-protein coupled receptor signaling pathway AnnotationPropagation P GO:0004930 G-protein coupled receptor activity IDA GO:0015031 protein transport AnnotationPropagation P GO:0008565 protein transporter activity IBA GO:0015721 bile acid and bile salt transport AnnotationPropagation P GO:0015125 bile acid transmembrane transporter activity IBA GO:1905039 carboxylic acid transmembrane transport AnnotationPropagation P GO:0015125 bile acid transmembrane transporter activity IBA GO:0098664 G-protein coupled serotonin receptor signaling pathway AnnotationPropagation P GO:0004993 G-protein coupled serotonin receptor activity IBA GO:0005623 cell AnnotationPropagation C GO:0051281 positive regulation of release of sequestered calcium ion into cytosol ISS GO:0010951 negative regulation of endopeptidase activity AnnotationPropagation P GO:0004867 serine-type endopeptidase inhibitor activity IDA GO:0006412 translation AnnotationPropagation P GO:0030533 triplet codon-amino acid adaptor activity ISS GO:0043547 positive regulation of GTPase activity AnnotationPropagation P GO:0005096 GTPase activator activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0006606 protein import into nucleus IBA GO:0005623 cell AnnotationPropagation C GO:0006606 protein import into nucleus IBA GO:0001510 RNA methylation AnnotationPropagation P GO:0120048 U6 snRNA (adenine-(43)-N(6))-methyltransferase activity ISS GO:0000122 negative regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IBA GO:0005622 intracellular AnnotationPropagation C GO:0006405 RNA export from nucleus IBA GO:0005623 cell AnnotationPropagation C GO:0006405 RNA export from nucleus IBA GO:0043666 regulation of phosphoprotein phosphatase activity AnnotationPropagation P GO:0019888 protein phosphatase regulator activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0031098 stress-activated protein kinase signaling cascade IBA GO:1903507 negative regulation of nucleic acid-templated transcription AnnotationPropagation P GO:0003714 transcription corepressor activity IBA GO:0098655 cation transmembrane transport AnnotationPropagation P GO:0005261 cation channel activity IBA GO:0015914 phospholipid transport AnnotationPropagation P GO:1990050 phosphatidic acid transporter activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway ISS GO:0005623 cell AnnotationPropagation C GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway ISS GO:0016567 protein ubiquitination AnnotationPropagation P GO:0061630 ubiquitin protein ligase activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0007249 I-kappaB kinase/NF-kappaB signaling IBA GO:0007186 G-protein coupled receptor signaling pathway AnnotationPropagation P GO:0008020 G-protein coupled photoreceptor activity IBA GO:0009584 detection of visible light AnnotationPropagation P GO:0008020 G-protein coupled photoreceptor activity IBA GO:0016567 protein ubiquitination AnnotationPropagation P GO:0061630 ubiquitin protein ligase activity IBA GO:0007165 signal transduction AnnotationPropagation P GO:0004888 transmembrane signaling receptor activity IBA GO:0005623 cell AnnotationPropagation C GO:0070050 neuron cellular homeostasis IMP GO:0016567 protein ubiquitination AnnotationPropagation P GO:0061630 ubiquitin protein ligase activity IBA GO:0070588 calcium ion transmembrane transport AnnotationPropagation P GO:0005432 calcium:sodium antiporter activity IBA GO:0035725 sodium ion transmembrane transport AnnotationPropagation P GO:0005432 calcium:sodium antiporter activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0047496 vesicle transport along microtubule IBA GO:0005623 cell AnnotationPropagation C GO:0047496 vesicle transport along microtubule IBA GO:0034969 histone arginine methylation AnnotationPropagation P GO:0008469 histone-arginine N-methyltransferase activity IBA GO:0035246 peptidyl-arginine N-methylation AnnotationPropagation P GO:0008469 histone-arginine N-methyltransferase activity IBA GO:0016567 protein ubiquitination AnnotationPropagation P GO:0061630 ubiquitin protein ligase activity IBA GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting IBA GO:0006412 translation AnnotationPropagation P GO:0030533 triplet codon-amino acid adaptor activity ISS GO:0035725 sodium ion transmembrane transport AnnotationPropagation P GO:0008510 sodium:bicarbonate symporter activity IBA GO:0015701 bicarbonate transport AnnotationPropagation P GO:0008510 sodium:bicarbonate symporter activity IBA GO:0098656 anion transmembrane transport AnnotationPropagation P GO:0008510 sodium:bicarbonate symporter activity IBA GO:0032259 methylation AnnotationPropagation P GO:0017096 acetylserotonin O-methyltransferase activity IBA GO:0035725 sodium ion transmembrane transport AnnotationPropagation P GO:0008510 sodium:bicarbonate symporter activity IBA GO:0015701 bicarbonate transport AnnotationPropagation P GO:0008510 sodium:bicarbonate symporter activity IBA GO:0098656 anion transmembrane transport AnnotationPropagation P GO:0008510 sodium:bicarbonate symporter activity IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0016618 hydroxypyruvate reductase activity IBA GO:1903507 negative regulation of nucleic acid-templated transcription AnnotationPropagation P GO:0003714 transcription corepressor activity IBA GO:0006508 proteolysis AnnotationPropagation P GO:0004185 serine-type carboxypeptidase activity IBA GO:0010951 negative regulation of endopeptidase activity AnnotationPropagation P GO:0004867 serine-type endopeptidase inhibitor activity IBA GO:0006366 transcription by RNA polymerase II AnnotationPropagation P GO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IBA GO:0045944 positive regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IBA GO:0006412 translation AnnotationPropagation P GO:0030533 triplet codon-amino acid adaptor activity ISS GO:0006165 nucleoside diphosphate phosphorylation AnnotationPropagation P GO:0004550 nucleoside diphosphate kinase activity IBA GO:0006508 proteolysis AnnotationPropagation P GO:0004222 metalloendopeptidase activity ISS GO:0043547 positive regulation of GTPase activity AnnotationPropagation P GO:0005096 GTPase activator activity IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0048244 phytanoyl-CoA dioxygenase activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0006408 snRNA export from nucleus IBA GO:0005623 cell AnnotationPropagation C GO:0006408 snRNA export from nucleus IBA GO:0006470 protein dephosphorylation AnnotationPropagation P GO:0004721 phosphoprotein phosphatase activity IBA GO:0006366 transcription by RNA polymerase II AnnotationPropagation P GO:0001105 RNA polymerase II transcription coactivator activity IBA GO:0045944 positive regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0001105 RNA polymerase II transcription coactivator activity IBA GO:0055085 transmembrane transport AnnotationPropagation P GO:0022857 transmembrane transporter activity IBA GO:0043547 positive regulation of GTPase activity AnnotationPropagation P GO:0005096 GTPase activator activity IBA GO:0007165 signal transduction AnnotationPropagation P GO:0004888 transmembrane signaling receptor activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0006886 intracellular protein transport IBA GO:0005623 cell AnnotationPropagation C GO:0006886 intracellular protein transport IBA GO:0006182 cGMP biosynthetic process AnnotationPropagation P GO:0004383 guanylate cyclase activity IBA GO:0005623 cell AnnotationPropagation C GO:0007204 positive regulation of cytosolic calcium ion concentration IBA GO:0007186 G-protein coupled receptor signaling pathway AnnotationPropagation P GO:0008020 G-protein coupled photoreceptor activity IBA GO:0009584 detection of visible light AnnotationPropagation P GO:0008020 G-protein coupled photoreceptor activity IBA GO:0016311 dephosphorylation AnnotationPropagation P GO:0008195 phosphatidate phosphatase activity IBA GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA GO:0007186 G-protein coupled receptor signaling pathway AnnotationPropagation P GO:0001594 trace-amine receptor activity IBA GO:0000781 chromosome, telomeric region AnnotationPropagation C GO:0006348 chromatin silencing at telomere IBA GO:0071805 potassium ion transmembrane transport AnnotationPropagation P GO:0015379 potassium:chloride symporter activity IBA GO:1902476 chloride transmembrane transport AnnotationPropagation P GO:0015379 potassium:chloride symporter activity IBA GO:0043086 negative regulation of catalytic activity AnnotationPropagation P GO:0019212 phosphatase inhibitor activity IBA GO:1904667 negative regulation of ubiquitin protein ligase activity AnnotationPropagation P GO:1990948 ubiquitin ligase inhibitor activity ISS GO:0005622 intracellular AnnotationPropagation C GO:0006886 intracellular protein transport IBA GO:0005623 cell AnnotationPropagation C GO:0006886 intracellular protein transport IBA GO:0031284 positive regulation of guanylate cyclase activity AnnotationPropagation P GO:0030250 guanylate cyclase activator activity ISS GO:0043547 positive regulation of GTPase activity AnnotationPropagation P GO:0005096 GTPase activator activity IBA GO:0007165 signal transduction AnnotationPropagation P GO:0004888 transmembrane signaling receptor activity IBA GO:0015931 nucleobase-containing compound transport AnnotationPropagation P GO:0005338 nucleotide-sugar transmembrane transporter activity IBA GO:0055085 transmembrane transport AnnotationPropagation P GO:0005338 nucleotide-sugar transmembrane transporter activity IBA GO:1901264 carbohydrate derivative transport AnnotationPropagation P GO:0005338 nucleotide-sugar transmembrane transporter activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0007266 Rho protein signal transduction IBA GO:0007186 G-protein coupled receptor signaling pathway AnnotationPropagation P GO:0008020 G-protein coupled photoreceptor activity IBA GO:0009584 detection of visible light AnnotationPropagation P GO:0008020 G-protein coupled photoreceptor activity IBA GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway AnnotationPropagation P GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity IBA GO:0009967 positive regulation of signal transduction AnnotationPropagation P GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity IBA GO:0098793 presynapse AnnotationPropagation C GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane IBA GO:0006508 proteolysis AnnotationPropagation P GO:0034722 gamma-glutamyl-peptidase activity IBA GO:0005739 mitochondrion AnnotationPropagation C GO:0033617 mitochondrial respiratory chain complex IV assembly ISS GO:0032259 methylation AnnotationPropagation P GO:0008171 O-methyltransferase activity ISS GO:0005622 intracellular AnnotationPropagation C GO:0031098 stress-activated protein kinase signaling cascade IBA GO:0006508 proteolysis AnnotationPropagation P GO:0004175 endopeptidase activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0010970 transport along microtubule IBA GO:0005623 cell AnnotationPropagation C GO:0010970 transport along microtubule IBA GO:0005622 intracellular AnnotationPropagation C GO:0035556 intracellular signal transduction IBA GO:0061025 membrane fusion AnnotationPropagation P GO:0005484 SNAP receptor activity IBA GO:0006278 RNA-dependent DNA biosynthetic process AnnotationPropagation P GO:0003964 RNA-directed DNA polymerase activity IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor IPI GO:0007186 G-protein coupled receptor signaling pathway AnnotationPropagation P GO:0008020 G-protein coupled photoreceptor activity IBA GO:0009584 detection of visible light AnnotationPropagation P GO:0008020 G-protein coupled photoreceptor activity IBA GO:0007186 G-protein coupled receptor signaling pathway AnnotationPropagation P GO:0008020 G-protein coupled photoreceptor activity IBA GO:0009584 detection of visible light AnnotationPropagation P GO:0008020 G-protein coupled photoreceptor activity IBA GO:0043666 regulation of phosphoprotein phosphatase activity AnnotationPropagation P GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0006886 intracellular protein transport IBA GO:0005623 cell AnnotationPropagation C GO:0006886 intracellular protein transport IBA GO:0010469 regulation of signaling receptor activity AnnotationPropagation P GO:0008083 growth factor activity IBA GO:0016310 phosphorylation AnnotationPropagation P GO:0004020 adenylylsulfate kinase activity IBA GO:0043547 positive regulation of GTPase activity AnnotationPropagation P GO:0005096 GTPase activator activity IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0008395 steroid hydroxylase activity IBA GO:0005623 cell AnnotationPropagation C GO:0046716 muscle cell cellular homeostasis IGI GO:0043547 positive regulation of GTPase activity AnnotationPropagation P GO:0005096 GTPase activator activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0032402 melanosome transport IMP GO:0005623 cell AnnotationPropagation C GO:0032402 melanosome transport IMP GO:0032515 negative regulation of phosphoprotein phosphatase activity AnnotationPropagation P GO:0004865 protein serine/threonine phosphatase inhibitor activity IBA GO:1902476 chloride transmembrane transport AnnotationPropagation P GO:0005229 intracellular calcium activated chloride channel activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0006886 intracellular protein transport IBA GO:0005623 cell AnnotationPropagation C GO:0006886 intracellular protein transport IBA GO:0006355 regulation of transcription, DNA-templated AnnotationPropagation P GO:0003700 DNA binding transcription factor activity IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0008395 steroid hydroxylase activity IBA GO:0043547 positive regulation of GTPase activity AnnotationPropagation P GO:0005096 GTPase activator activity IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0004800 thyroxine 5'-deiodinase activity IDA GO:0019221 cytokine-mediated signaling pathway AnnotationPropagation P GO:0004896 cytokine receptor activity IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0016491 oxidoreductase activity IBA GO:1903506 regulation of nucleic acid-templated transcription AnnotationPropagation P GO:0003713 transcription coactivator activity IBA GO:0035247 peptidyl-arginine omega-N-methylation AnnotationPropagation P GO:0035241 protein-arginine omega-N monomethyltransferase activity IBA GO:0016567 protein ubiquitination AnnotationPropagation P GO:0061630 ubiquitin protein ligase activity IBA GO:0007165 signal transduction AnnotationPropagation P GO:0004888 transmembrane signaling receptor activity IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0008395 steroid hydroxylase activity IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0008395 steroid hydroxylase activity IBA GO:0016055 Wnt signaling pathway AnnotationPropagation P GO:0042813 Wnt-activated receptor activity IBA GO:0043547 positive regulation of GTPase activity AnnotationPropagation P GO:0005096 GTPase activator activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0006886 intracellular protein transport IBA GO:0005623 cell AnnotationPropagation C GO:0006886 intracellular protein transport IBA GO:0016567 protein ubiquitination AnnotationPropagation P GO:0061630 ubiquitin protein ligase activity IBA GO:0098655 cation transmembrane transport AnnotationPropagation P GO:0022850 serotonin-gated cation-selective channel activity IBA GO:0007165 signal transduction AnnotationPropagation P GO:0022850 serotonin-gated cation-selective channel activity IBA GO:0015718 monocarboxylic acid transport AnnotationPropagation P GO:0008028 monocarboxylic acid transmembrane transporter activity IBA GO:1905039 carboxylic acid transmembrane transport AnnotationPropagation P GO:0008028 monocarboxylic acid transmembrane transporter activity IBA GO:0016567 protein ubiquitination AnnotationPropagation P GO:0061630 ubiquitin protein ligase activity IBA GO:0055085 transmembrane transport AnnotationPropagation P GO:0015267 channel activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0006913 nucleocytoplasmic transport IBA GO:0005623 cell AnnotationPropagation C GO:0006913 nucleocytoplasmic transport IBA GO:0010469 regulation of signaling receptor activity AnnotationPropagation P GO:0005179 hormone activity IBA GO:0016311 dephosphorylation AnnotationPropagation P GO:0004445 inositol-polyphosphate 5-phosphatase activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0007264 small GTPase mediated signal transduction IBA GO:0005622 intracellular AnnotationPropagation C GO:0035556 intracellular signal transduction IBA GO:0005622 intracellular AnnotationPropagation C GO:0035556 intracellular signal transduction IBA GO:0015825 L-serine transport AnnotationPropagation P GO:0015194 L-serine transmembrane transporter activity IBA GO:0098655 cation transmembrane transport AnnotationPropagation P GO:0015194 L-serine transmembrane transporter activity IBA GO:1902475 L-alpha-amino acid transmembrane transport AnnotationPropagation P GO:0015194 L-serine transmembrane transporter activity IBA GO:0007165 signal transduction AnnotationPropagation P GO:0004888 transmembrane signaling receptor activity IBA GO:0043547 positive regulation of GTPase activity AnnotationPropagation P GO:0005096 GTPase activator activity IBA GO:0006468 protein phosphorylation AnnotationPropagation P GO:0004674 protein serine/threonine kinase activity IBA GO:0006508 proteolysis AnnotationPropagation P GO:0004185 serine-type carboxypeptidase activity IBA GO:0043666 regulation of phosphoprotein phosphatase activity AnnotationPropagation P GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0035329 hippo signaling IMP GO:0007165 signal transduction AnnotationPropagation P GO:0004888 transmembrane signaling receptor activity IBA GO:0005623 cell AnnotationPropagation C GO:0099093 calcium export from the mitochondrion ISS GO:0035725 sodium ion transmembrane transport AnnotationPropagation P GO:0015319 sodium:inorganic phosphate symporter activity IBA GO:0016567 protein ubiquitination AnnotationPropagation P GO:0004842 ubiquitin-protein transferase activity IC GO:0005623 cell AnnotationPropagation C GO:0006874 cellular calcium ion homeostasis IBA GO:0006278 RNA-dependent DNA biosynthetic process AnnotationPropagation P GO:0003964 RNA-directed DNA polymerase activity IBA GO:0098664 G-protein coupled serotonin receptor signaling pathway AnnotationPropagation P GO:0004993 G-protein coupled serotonin receptor activity IBA GO:1903507 negative regulation of nucleic acid-templated transcription AnnotationPropagation P GO:0003714 transcription corepressor activity IBA GO:0006366 transcription by RNA polymerase II AnnotationPropagation P GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA GO:0045944 positive regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA GO:0043547 positive regulation of GTPase activity AnnotationPropagation P GO:0005096 GTPase activator activity IBA GO:0010951 negative regulation of endopeptidase activity AnnotationPropagation P GO:0004867 serine-type endopeptidase inhibitor activity IBA GO:0009967 positive regulation of signal transduction AnnotationPropagation P GO:0005070 SH3/SH2 adaptor activity IBA GO:0018108 peptidyl-tyrosine phosphorylation AnnotationPropagation P GO:0004713 protein tyrosine kinase activity ISS GO:0010951 negative regulation of endopeptidase activity AnnotationPropagation P GO:0004867 serine-type endopeptidase inhibitor activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0006886 intracellular protein transport IBA GO:0005623 cell AnnotationPropagation C GO:0006886 intracellular protein transport IBA GO:0007186 G-protein coupled receptor signaling pathway AnnotationPropagation P GO:0008020 G-protein coupled photoreceptor activity IBA GO:0009584 detection of visible light AnnotationPropagation P GO:0008020 G-protein coupled photoreceptor activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0031098 stress-activated protein kinase signaling cascade IBA GO:0017148 negative regulation of translation AnnotationPropagation P GO:0000900 translation repressor activity, mRNA regulatory element binding ISS GO:0090481 pyrimidine nucleotide-sugar transmembrane transport AnnotationPropagation P GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity IBA GO:0033209 tumor necrosis factor-mediated signaling pathway AnnotationPropagation P GO:0005031 tumor necrosis factor-activated receptor activity IBA GO:0012501 programmed cell death AnnotationPropagation P GO:0005031 tumor necrosis factor-activated receptor activity IBA GO:0036065 fucosylation AnnotationPropagation P GO:0046920 alpha-(1->3)-fucosyltransferase activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0006886 intracellular protein transport IBA GO:0005623 cell AnnotationPropagation C GO:0006886 intracellular protein transport IBA GO:0005622 intracellular AnnotationPropagation C GO:0007264 small GTPase mediated signal transduction IMP GO:0005622 intracellular AnnotationPropagation C GO:0016197 endosomal transport IBA GO:0005623 cell AnnotationPropagation C GO:0016197 endosomal transport IBA GO:0000165 MAPK cascade AnnotationPropagation P GO:0008349 MAP kinase kinase kinase kinase activity IBA GO:0000185 activation of MAPKKK activity AnnotationPropagation P GO:0008349 MAP kinase kinase kinase kinase activity IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0016491 oxidoreductase activity IBA GO:0006855 drug transmembrane transport AnnotationPropagation P GO:0015137 citrate transmembrane transporter activity IBA GO:0015746 citrate transport AnnotationPropagation P GO:0015137 citrate transmembrane transporter activity IBA GO:0035674 tricarboxylic acid transmembrane transport AnnotationPropagation P GO:0015137 citrate transmembrane transporter activity IBA GO:0006508 proteolysis AnnotationPropagation P GO:0004175 endopeptidase activity IBA GO:0006366 transcription by RNA polymerase II AnnotationPropagation P GO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IBA GO:0045944 positive regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IBA GO:0005622 intracellular AnnotationPropagation C GO:0045039 protein import into mitochondrial inner membrane ISS GO:0005623 cell AnnotationPropagation C GO:0045039 protein import into mitochondrial inner membrane ISS GO:0005739 mitochondrion AnnotationPropagation C GO:0045039 protein import into mitochondrial inner membrane ISS GO:0006355 regulation of transcription, DNA-templated AnnotationPropagation P GO:0003700 DNA binding transcription factor activity IBA GO:0006278 RNA-dependent DNA biosynthetic process AnnotationPropagation P GO:0003964 RNA-directed DNA polymerase activity IBA GO:0007165 signal transduction AnnotationPropagation P GO:0004888 transmembrane signaling receptor activity IBA GO:0000413 protein peptidyl-prolyl isomerization AnnotationPropagation P GO:0003755 peptidyl-prolyl cis-trans isomerase activity IBA GO:0006508 proteolysis AnnotationPropagation P GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process IBA GO:0006915 apoptotic process AnnotationPropagation P GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process IBA GO:0016311 dephosphorylation AnnotationPropagation P GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity IBA GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process AnnotationPropagation P GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity IBA GO:0007165 signal transduction AnnotationPropagation P GO:0004888 transmembrane signaling receptor activity IBA GO:1903506 regulation of nucleic acid-templated transcription AnnotationPropagation P GO:0003713 transcription coactivator activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0031098 stress-activated protein kinase signaling cascade IBA GO:0007165 signal transduction AnnotationPropagation P GO:0004888 transmembrane signaling receptor activity IBA GO:0016567 protein ubiquitination AnnotationPropagation P GO:0061630 ubiquitin protein ligase activity IBA GO:0010951 negative regulation of endopeptidase activity AnnotationPropagation P GO:0004867 serine-type endopeptidase inhibitor activity IBA GO:0045332 phospholipid translocation AnnotationPropagation P GO:0004012 phospholipid-translocating ATPase activity IBA GO:0016567 protein ubiquitination AnnotationPropagation P GO:0061630 ubiquitin protein ligase activity IBA GO:0098655 cation transmembrane transport AnnotationPropagation P GO:0022850 serotonin-gated cation-selective channel activity IBA GO:0007165 signal transduction AnnotationPropagation P GO:0022850 serotonin-gated cation-selective channel activity IBA GO:0007165 signal transduction AnnotationPropagation P GO:0004888 transmembrane signaling receptor activity IBA GO:0006508 proteolysis AnnotationPropagation P GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process IBA GO:0006915 apoptotic process AnnotationPropagation P GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process IBA GO:0031284 positive regulation of guanylate cyclase activity AnnotationPropagation P GO:0008048 calcium sensitive guanylate cyclase activator activity IDA GO:0015718 monocarboxylic acid transport AnnotationPropagation P GO:0008028 monocarboxylic acid transmembrane transporter activity IBA GO:1905039 carboxylic acid transmembrane transport AnnotationPropagation P GO:0008028 monocarboxylic acid transmembrane transporter activity IBA GO:0016567 protein ubiquitination AnnotationPropagation P GO:0061630 ubiquitin protein ligase activity IBA GO:0010469 regulation of signaling receptor activity AnnotationPropagation P GO:0008083 growth factor activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IBA GO:0016567 protein ubiquitination AnnotationPropagation P GO:0061630 ubiquitin protein ligase activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0031098 stress-activated protein kinase signaling cascade IBA GO:0005622 intracellular AnnotationPropagation C GO:0006606 protein import into nucleus IBA GO:0005623 cell AnnotationPropagation C GO:0006606 protein import into nucleus IBA GO:0000165 MAPK cascade AnnotationPropagation P GO:0004709 MAP kinase kinase kinase activity IBA GO:0000186 activation of MAPKK activity AnnotationPropagation P GO:0004709 MAP kinase kinase kinase activity IBA GO:0071577 zinc ion transmembrane transport AnnotationPropagation P GO:0005385 zinc ion transmembrane transporter activity ISS GO:0032147 activation of protein kinase activity AnnotationPropagation P GO:0030295 protein kinase activator activity ISS GO:0005739 mitochondrion AnnotationPropagation C GO:0007007 inner mitochondrial membrane organization IBA GO:0016310 phosphorylation AnnotationPropagation P GO:0050201 fucokinase activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0006405 RNA export from nucleus IBA GO:0005623 cell AnnotationPropagation C GO:0006405 RNA export from nucleus IBA GO:0043086 negative regulation of catalytic activity AnnotationPropagation P GO:0004857 enzyme inhibitor activity IBA GO:0005783 endoplasmic reticulum AnnotationPropagation C GO:0032469 endoplasmic reticulum calcium ion homeostasis IDA GO:0005623 cell AnnotationPropagation C GO:0032469 endoplasmic reticulum calcium ion homeostasis IDA GO:0005739 mitochondrion AnnotationPropagation C GO:0070124 mitochondrial translational initiation IBA GO:0007186 G-protein coupled receptor signaling pathway AnnotationPropagation P GO:0008020 G-protein coupled photoreceptor activity IBA GO:0009584 detection of visible light AnnotationPropagation P GO:0008020 G-protein coupled photoreceptor activity IBA GO:0016567 protein ubiquitination AnnotationPropagation P GO:0061630 ubiquitin protein ligase activity IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0008395 steroid hydroxylase activity IBA GO:0016311 dephosphorylation AnnotationPropagation P GO:0008253 5'-nucleotidase activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0031098 stress-activated protein kinase signaling cascade IBA GO:0006355 regulation of transcription, DNA-templated AnnotationPropagation P GO:0003700 DNA binding transcription factor activity IBA GO:0007165 signal transduction AnnotationPropagation P GO:0004888 transmembrane signaling receptor activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0016197 endosomal transport IBA GO:0005623 cell AnnotationPropagation C GO:0016197 endosomal transport IBA GO:0006412 translation AnnotationPropagation P GO:0030533 triplet codon-amino acid adaptor activity ISS GO:0006412 translation AnnotationPropagation P GO:0030533 triplet codon-amino acid adaptor activity ISS GO:0098664 G-protein coupled serotonin receptor signaling pathway AnnotationPropagation P GO:0004993 G-protein coupled serotonin receptor activity IBA GO:0016925 protein sumoylation AnnotationPropagation P GO:0019789 SUMO transferase activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0007254 JNK cascade IMP GO:0007165 signal transduction AnnotationPropagation P GO:0004888 transmembrane signaling receptor activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway IBA GO:0005623 cell AnnotationPropagation C GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway IBA GO:0005622 intracellular AnnotationPropagation C GO:0032402 melanosome transport IMP GO:0005623 cell AnnotationPropagation C GO:0032402 melanosome transport IMP GO:0016310 phosphorylation AnnotationPropagation P GO:0004020 adenylylsulfate kinase activity IBA GO:0005623 cell AnnotationPropagation C GO:0048488 synaptic vesicle endocytosis IBA GO:0045202 synapse AnnotationPropagation C GO:0048488 synaptic vesicle endocytosis IBA GO:0005622 intracellular AnnotationPropagation C GO:0048015 phosphatidylinositol-mediated signaling IBA GO:0005622 intracellular AnnotationPropagation C GO:0006406 mRNA export from nucleus IBA GO:0005623 cell AnnotationPropagation C GO:0006406 mRNA export from nucleus IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0016491 oxidoreductase activity IBA GO:0034969 histone arginine methylation AnnotationPropagation P GO:0008469 histone-arginine N-methyltransferase activity IBA GO:0035246 peptidyl-arginine N-methylation AnnotationPropagation P GO:0008469 histone-arginine N-methyltransferase activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0006913 nucleocytoplasmic transport IBA GO:0005623 cell AnnotationPropagation C GO:0006913 nucleocytoplasmic transport IBA GO:0005622 intracellular AnnotationPropagation C GO:0000055 ribosomal large subunit export from nucleus IBA GO:0005623 cell AnnotationPropagation C GO:0000055 ribosomal large subunit export from nucleus IBA GO:0016567 protein ubiquitination AnnotationPropagation P GO:0061630 ubiquitin protein ligase activity IBA GO:0006855 drug transmembrane transport AnnotationPropagation P GO:0015186 L-glutamine transmembrane transporter activity IBA GO:0006868 glutamine transport AnnotationPropagation P GO:0015186 L-glutamine transmembrane transporter activity IBA GO:0098655 cation transmembrane transport AnnotationPropagation P GO:0015186 L-glutamine transmembrane transporter activity IBA GO:1902475 L-alpha-amino acid transmembrane transport AnnotationPropagation P GO:0015186 L-glutamine transmembrane transporter activity IBA GO:0015718 monocarboxylic acid transport AnnotationPropagation P GO:0008028 monocarboxylic acid transmembrane transporter activity IBA GO:1905039 carboxylic acid transmembrane transport AnnotationPropagation P GO:0008028 monocarboxylic acid transmembrane transporter activity IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0003954 NADH dehydrogenase activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress ISS GO:0006366 transcription by RNA polymerase II AnnotationPropagation P GO:0001105 RNA polymerase II transcription coactivator activity IBA GO:0045944 positive regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0001105 RNA polymerase II transcription coactivator activity IBA GO:0016567 protein ubiquitination AnnotationPropagation P GO:0061630 ubiquitin protein ligase activity IBA GO:0019221 cytokine-mediated signaling pathway AnnotationPropagation P GO:0004896 cytokine receptor activity IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0004720 protein-lysine 6-oxidase activity ISS GO:0043547 positive regulation of GTPase activity AnnotationPropagation P GO:0005096 GTPase activator activity IBA GO:0071805 potassium ion transmembrane transport AnnotationPropagation P GO:0022841 potassium ion leak channel activity IBA GO:0007186 G-protein coupled receptor signaling pathway AnnotationPropagation P GO:0001594 trace-amine receptor activity IBA GO:0015031 protein transport AnnotationPropagation P GO:0008565 protein transporter activity IBA GO:0005829 cytosol AnnotationPropagation C GO:0002184 cytoplasmic translational termination IBA GO:0006412 translation AnnotationPropagation P GO:0030533 triplet codon-amino acid adaptor activity ISS GO:0006355 regulation of transcription, DNA-templated AnnotationPropagation P GO:0003700 DNA binding transcription factor activity IBA GO:0016567 protein ubiquitination AnnotationPropagation P GO:0061630 ubiquitin protein ligase activity IBA GO:0010951 negative regulation of endopeptidase activity AnnotationPropagation P GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity ISS GO:0031284 positive regulation of guanylate cyclase activity AnnotationPropagation P GO:0030250 guanylate cyclase activator activity ISS GO:0098664 G-protein coupled serotonin receptor signaling pathway AnnotationPropagation P GO:0004993 G-protein coupled serotonin receptor activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0031098 stress-activated protein kinase signaling cascade IBA GO:0071805 potassium ion transmembrane transport AnnotationPropagation P GO:0005242 inward rectifier potassium channel activity IDA GO:0006468 protein phosphorylation AnnotationPropagation P GO:0004674 protein serine/threonine kinase activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0006606 protein import into nucleus IBA GO:0005623 cell AnnotationPropagation C GO:0006606 protein import into nucleus IBA GO:0006356 regulation of transcription by RNA polymerase I AnnotationPropagation P GO:0001181 transcription factor activity, core RNA polymerase I binding IBA GO:0006165 nucleoside diphosphate phosphorylation AnnotationPropagation P GO:0004550 nucleoside diphosphate kinase activity IBA GO:0010469 regulation of signaling receptor activity AnnotationPropagation P GO:0005184 neuropeptide hormone activity IBA GO:0043666 regulation of phosphoprotein phosphatase activity AnnotationPropagation P GO:0019888 protein phosphatase regulator activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0006606 protein import into nucleus IBA GO:0005623 cell AnnotationPropagation C GO:0006606 protein import into nucleus IBA GO:0006855 drug transmembrane transport AnnotationPropagation P GO:0015238 drug transmembrane transporter activity IBA GO:0043085 positive regulation of catalytic activity AnnotationPropagation P GO:0008047 enzyme activator activity IBA GO:0035725 sodium ion transmembrane transport AnnotationPropagation P GO:0008510 sodium:bicarbonate symporter activity IBA GO:0015701 bicarbonate transport AnnotationPropagation P GO:0008510 sodium:bicarbonate symporter activity IBA GO:0098656 anion transmembrane transport AnnotationPropagation P GO:0008510 sodium:bicarbonate symporter activity IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0008395 steroid hydroxylase activity IBA GO:0071805 potassium ion transmembrane transport AnnotationPropagation P GO:0015271 outward rectifier potassium channel activity IBA GO:0015718 monocarboxylic acid transport AnnotationPropagation P GO:0008028 monocarboxylic acid transmembrane transporter activity IBA GO:1905039 carboxylic acid transmembrane transport AnnotationPropagation P GO:0008028 monocarboxylic acid transmembrane transporter activity IBA GO:0016310 phosphorylation AnnotationPropagation P GO:0016301 kinase activity IBA GO:0006508 proteolysis AnnotationPropagation P GO:0004185 serine-type carboxypeptidase activity IBA GO:0006412 translation AnnotationPropagation P GO:0030533 triplet codon-amino acid adaptor activity ISS GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0030267 glyoxylate reductase (NADP) activity IBA GO:0006366 transcription by RNA polymerase II AnnotationPropagation P GO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IBA GO:0045944 positive regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IBA GO:0006508 proteolysis AnnotationPropagation P GO:0004175 endopeptidase activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0006886 intracellular protein transport IBA GO:0005623 cell AnnotationPropagation C GO:0006886 intracellular protein transport IBA GO:0005622 intracellular AnnotationPropagation C GO:0035721 intraciliary retrograde transport IBA GO:0005623 cell AnnotationPropagation C GO:0035721 intraciliary retrograde transport IBA GO:0005929 cilium AnnotationPropagation C GO:0035721 intraciliary retrograde transport IBA GO:0015914 phospholipid transport AnnotationPropagation P GO:0017128 phospholipid scramblase activity IBA GO:0017121 phospholipid scrambling AnnotationPropagation P GO:0017128 phospholipid scramblase activity IBA GO:0006470 protein dephosphorylation AnnotationPropagation P GO:0004721 phosphoprotein phosphatase activity IBA GO:0016310 phosphorylation AnnotationPropagation P GO:0051731 polynucleotide 5'-hydroxyl-kinase activity IBA GO:0016310 phosphorylation AnnotationPropagation P GO:0004020 adenylylsulfate kinase activity IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0047134 protein-disulfide reductase activity IBA GO:0006470 protein dephosphorylation AnnotationPropagation P GO:0004721 phosphoprotein phosphatase activity IBA GO:0006412 translation AnnotationPropagation P GO:0030533 triplet codon-amino acid adaptor activity ISS GO:0019722 calcium-mediated signaling AnnotationPropagation P GO:0015278 calcium-release channel activity IDA GO:0051209 release of sequestered calcium ion into cytosol AnnotationPropagation P GO:0015278 calcium-release channel activity IDA GO:0015711 organic anion transport AnnotationPropagation P GO:0015347 sodium-independent organic anion transmembrane transporter activity IBA GO:0098656 anion transmembrane transport AnnotationPropagation P GO:0015347 sodium-independent organic anion transmembrane transporter activity IBA GO:0007165 signal transduction AnnotationPropagation P GO:0004888 transmembrane signaling receptor activity IBA GO:0005623 cell AnnotationPropagation C GO:0071911 synchronous neurotransmitter secretion IMP GO:0098793 presynapse AnnotationPropagation C GO:0071911 synchronous neurotransmitter secretion IMP GO:0045202 synapse AnnotationPropagation C GO:0071911 synchronous neurotransmitter secretion IMP GO:0032259 methylation AnnotationPropagation P GO:0008757 S-adenosylmethionine-dependent methyltransferase activity ISS GO:0015711 organic anion transport AnnotationPropagation P GO:0008514 organic anion transmembrane transporter activity IBA GO:0098656 anion transmembrane transport AnnotationPropagation P GO:0008514 organic anion transmembrane transporter activity IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0016491 oxidoreductase activity IBA GO:0071805 potassium ion transmembrane transport AnnotationPropagation P GO:0022841 potassium ion leak channel activity IBA GO:0006366 transcription by RNA polymerase II AnnotationPropagation P GO:0001105 RNA polymerase II transcription coactivator activity IBA GO:0045944 positive regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0001105 RNA polymerase II transcription coactivator activity IBA GO:0006412 translation AnnotationPropagation P GO:0030533 triplet codon-amino acid adaptor activity ISS GO:0043547 positive regulation of GTPase activity AnnotationPropagation P GO:0005096 GTPase activator activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0006610 ribosomal protein import into nucleus IBA GO:0005623 cell AnnotationPropagation C GO:0006610 ribosomal protein import into nucleus IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0008395 steroid hydroxylase activity IBA GO:0016567 protein ubiquitination AnnotationPropagation P GO:0061630 ubiquitin protein ligase activity IBA GO:0043547 positive regulation of GTPase activity AnnotationPropagation P GO:0005096 GTPase activator activity IBA GO:0031167 rRNA methylation AnnotationPropagation P GO:0071424 rRNA (cytosine-N4-)-methyltransferase activity IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0008137 NADH dehydrogenase (ubiquinone) activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage IBA GO:0005623 cell AnnotationPropagation C GO:0048488 synaptic vesicle endocytosis IBA GO:0045202 synapse AnnotationPropagation C GO:0048488 synaptic vesicle endocytosis IBA GO:0043547 positive regulation of GTPase activity AnnotationPropagation P GO:0005096 GTPase activator activity IBA GO:0006457 protein folding AnnotationPropagation P GO:0044183 protein binding involved in protein folding IBA GO:0007165 signal transduction AnnotationPropagation P GO:0004871 signal transducer activity IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0008395 steroid hydroxylase activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0007264 small GTPase mediated signal transduction IBA GO:0010951 negative regulation of endopeptidase activity AnnotationPropagation P GO:0004867 serine-type endopeptidase inhibitor activity IBA GO:0015914 phospholipid transport AnnotationPropagation P GO:0017128 phospholipid scramblase activity IBA GO:0017121 phospholipid scrambling AnnotationPropagation P GO:0017128 phospholipid scramblase activity IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0008395 steroid hydroxylase activity IBA GO:0005623 cell AnnotationPropagation C GO:0007035 vacuolar acidification IBA GO:1902476 chloride transmembrane transport AnnotationPropagation P GO:0005254 chloride channel activity IBA GO:0007165 signal transduction AnnotationPropagation P GO:0004888 transmembrane signaling receptor activity IBA GO:0046710 GDP metabolic process AnnotationPropagation P GO:0004385 guanylate kinase activity IBA GO:0046939 nucleotide phosphorylation AnnotationPropagation P GO:0004385 guanylate kinase activity IBA GO:0046037 GMP metabolic process AnnotationPropagation P GO:0004385 guanylate kinase activity IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0016491 oxidoreductase activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0008333 endosome to lysosome transport ISS GO:0005623 cell AnnotationPropagation C GO:0008333 endosome to lysosome transport ISS GO:0016311 dephosphorylation AnnotationPropagation P GO:0008253 5'-nucleotidase activity IBA GO:0015711 organic anion transport AnnotationPropagation P GO:0015347 sodium-independent organic anion transmembrane transporter activity IBA GO:0098656 anion transmembrane transport AnnotationPropagation P GO:0015347 sodium-independent organic anion transmembrane transporter activity IBA GO:0043410 positive regulation of MAPK cascade AnnotationPropagation P GO:0005078 MAP-kinase scaffold activity IBA GO:0016020 membrane AnnotationPropagation C GO:0001766 membrane raft polarization IBA GO:0006591 ornithine metabolic process AnnotationPropagation P GO:0004585 ornithine carbamoyltransferase activity IBA GO:0016310 phosphorylation AnnotationPropagation P GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity IBA GO:0050790 regulation of catalytic activity AnnotationPropagation P GO:0048270 methionine adenosyltransferase regulator activity ISS GO:0016311 dephosphorylation AnnotationPropagation P GO:0008253 5'-nucleotidase activity IBA GO:0000375 RNA splicing, via transesterification reactions AnnotationPropagation P GO:0000386 second spliceosomal transesterification activity IBA GO:0007165 signal transduction AnnotationPropagation P GO:0004888 transmembrane signaling receptor activity IBA GO:0010951 negative regulation of endopeptidase activity AnnotationPropagation P GO:0004867 serine-type endopeptidase inhibitor activity IDA GO:0005622 intracellular AnnotationPropagation C GO:0006886 intracellular protein transport IBA GO:0005623 cell AnnotationPropagation C GO:0006886 intracellular protein transport IBA GO:0005622 intracellular AnnotationPropagation C GO:0031098 stress-activated protein kinase signaling cascade IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0008395 steroid hydroxylase activity IBA GO:0043547 positive regulation of GTPase activity AnnotationPropagation P GO:0005096 GTPase activator activity IBA GO:0045859 regulation of protein kinase activity AnnotationPropagation P GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0017150 tRNA dihydrouridine synthase activity IBA GO:0002943 tRNA dihydrouridine synthesis AnnotationPropagation P GO:0017150 tRNA dihydrouridine synthase activity IBA GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0016491 oxidoreductase activity IBA GO:0098655 cation transmembrane transport AnnotationPropagation P GO:0022850 serotonin-gated cation-selective channel activity IBA GO:0007165 signal transduction AnnotationPropagation P GO:0022850 serotonin-gated cation-selective channel activity IBA GO:0015718 monocarboxylic acid transport AnnotationPropagation P GO:0008028 monocarboxylic acid transmembrane transporter activity IBA GO:1905039 carboxylic acid transmembrane transport AnnotationPropagation P GO:0008028 monocarboxylic acid transmembrane transporter activity IBA GO:0035269 protein O-linked mannosylation AnnotationPropagation P GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity IBA GO:0043547 positive regulation of GTPase activity AnnotationPropagation P GO:0005096 GTPase activator activity IBA GO:1903507 negative regulation of nucleic acid-templated transcription AnnotationPropagation P GO:0003714 transcription corepressor activity IBA GO:0016567 protein ubiquitination AnnotationPropagation P GO:0061630 ubiquitin protein ligase activity IBA GO:0005622 intracellular AnnotationPropagation C GO:0031098 stress-activated protein kinase signaling cascade IBA GO:0043547 positive regulation of GTPase activity AnnotationPropagation P GO:0005096 GTPase activator activity IBA